13-deoxydoxorubicin Uses, Dosage, Side Effects and more
GPX-100 is an anthracycline anticancer drug that belongs to the family of drugs called antitumor antibiotics.
| Attribute | Details |
|---|---|
| Trade Name | 13-deoxydoxorubicin |
| Generic | 13-deoxydoxorubicin |
| Type | |
| Formula | C27H31NO10 |
| Weight | Average: 529.542 Monoisotopic: 529.194796202 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in breast cancer and cancer/tumors (unspecified).
How 13-deoxydoxorubicin works
As an anthracycline, GPX-100 has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: GPX-100 forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes.
