13-deoxydoxorubicin
13-deoxydoxorubicin Uses, Dosage, Side Effects, Food Interaction and all others data.
GPX-100 is an anthracycline anticancer drug that belongs to the family of drugs called antitumor antibiotics.
Trade Name | 13-deoxydoxorubicin |
Generic | 13-deoxydoxorubicin |
Type | |
Formula | C27H31NO10 |
Weight | Average: 529.542 Monoisotopic: 529.194796202 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in breast cancer and cancer/tumors (unspecified).
How 13-deoxydoxorubicin works
As an anthracycline, GPX-100 has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: GPX-100 forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes.
Innovators Monograph
You find simplified version here 13-deoxydoxorubicin