4-Dimethylaminophenazone
4-Dimethylaminophenazone Uses, Dosage, Side Effects, Food Interaction and all others data.
4-Dimethylaminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis. In biomedical applications, radiolabelled (13C-labeled) aminophenazone has been used in breath tests to measure the cytochrome P-450 metabolic activity in liver function tests.
4-Dimethylaminophenazone exhibits analgesic, anti-inflammatory, and antipyretic properties.
Trade Name | 4-Dimethylaminophenazone |
Generic | Aminophenazone |
Aminophenazone Other Names | (Dimethylamino)phenazone, 4-Dimethylaminoantipyrine, 4-Dimethylaminophenazone, Aminofenazona, Aminofenazone, Aminophenazon, Aminophenazone, Aminophenazonum, Aminopyrine, Dimethylaminoantipyrine, Dimethylaminoazophene, Dimethylaminophenazon, Dimethylaminophenazone, Dimethylaminophenyldimethylpyrazolone, Dipyrine |
Type | |
Formula | C13H17N3O |
Weight | Average: 231.2936 Monoisotopic: 231.137162181 |
Groups | Approved, Withdrawn |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
4-Dimethylaminophenazone is an analgesic drug used to treat acute migraine attacks in combination with ergotamine and caffeine.
Formerly widely used as an antipyretic and analgesic in rheumatism, neuritis, and common colds. Currently used to measure total body water.
4-Dimethylaminophenazone is also used to associated treatment for these conditions: Acute Migraine
How 4-Dimethylaminophenazone works
4-Dimethylaminophenazone is metabolized very slowly by normal newborn babies. In older infants, a higher amount of exhaled 13-CO2 is observed.
Toxicity
Can cause life-threatening agranulocytosis.
Innovators Monograph
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