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4'-Methylene-5,8,10-trideazaaminopterin Uses, Dosage, Side Effects and more

CH-1504 is a an antirheumatic agent that has been shown in vitro to be a nonpolyglutamylatable and nonhydroxylatable antifolate that is more efficiently taken up into cells by the reduced folate carrier (RFC) system than is Methotrexate. It has been investigated for the treatment of Rheumatoid Arthritis (phase II).

Attribute Details
Trade Name 4'-Methylene-5,8,10-trideazaaminopterin
Generic 4'-Methylene-5,8,10-trideazaaminopterin
Type
Formula C23H23N5O5
Weight Average: 449.467
Monoisotopic: 449.169918861
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: January 7, 2025 at 1:49 am
   

Uses

Investigated for use/treatment in inflammatory disorders (unspecified), psoriasis and psoriatic disorders, and rheumatoid arthritis.

Innovators Monograph

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