7-dichlor-8-hydroxychinolin

7-dichlor-8-hydroxychinolin Uses, Dosage, Side Effects, Food Interaction and all others data.

7-dichlor-8-hydroxychinolin is a synthetic antibacterial compound. 7-dichlor-8-hydroxychinolin is a compound used in some shampoos for the treatment of dandruff and seborrheic dermatitis of the scalp.

7-dichlor-8-hydroxychinolin has an antibacterial action, inhibiting the growth of gram-positive as well as some gram-negative organisms. Also, chloroxine has shown some antifungal activity against certain dermatophytes and yeasts.

7-dichlor-8-hydroxychinolin
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Trade Name	7-dichlor-8-hydroxychinolin
Generic	Chloroxine
Chloroxine Other Names	5,7-dichlor-8-hydroxychinolin, 5,7-dichlorooxine, 5,7-dichloroxine, Chloroxine, Chlorquinol
Type
Formula	C₉H₅Cl₂NO
Weight	Average: 214.048 Monoisotopic: 212.974819201
Groups	Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

7-dichlor-8-hydroxychinolin is an antibacterial agent used for the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp.

Used in the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp.

7-dichlor-8-hydroxychinolin is also used to associated treatment for these conditions: Dermatitis, Dermatosis, Fungal skin infection, Intertrigo, Skin Infections, Bacterial

How 7-dichlor-8-hydroxychinolin works

Although the mechanism of action is not understood, chloroxine may slow down mitotic activity in the epidermis, thereby reducing excessive scaling associated with dandruff or seborrheic dermatitis of the scalp. 7-dichlor-8-hydroxychinolin induces SOS-DNA repair in E. coli, so chloroxine may be genotoxic to bacteria.