Aspatrend

Aspatrend Uses, Dosage, Side Effects, Food Interaction and all others data.

Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine. L-Aspatrend allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.

A non-essential and nonprotein amino acid, ornithine is critical for the production of the body's proteins, enzymes and muscle tissue. Aspatrend plays a central role in the urea cycle and is important for the disposal of excess nitrogen (ammonia). Aspatrend is the starting point for the synthesis of many polyamines such as putrescine and spermine. Aspatrend supplements are claimed to enhance the release of growth hormone and to burn excess body fat. Aspatrend is necessary for proper immune function and good liver function.

Trade Name Aspatrend
Generic Ornithine
Ornithine Other Names (S)-ornithine, L-Ornithine, levo-ornithine, Ornithine, Ornithinum, Ornitina
Type
Formula C5H12N2O2
Weight Average: 132.161
Monoisotopic: 132.089877638
Groups Approved, Nutraceutical
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Aspatrend
Aspatrend

Uses

Aspatrend is an amino acid commonly found as a component in total parenteral nutrition.

Used for nutritional supplementation, also for treating dietary shortage or imbalance. It has been claimed that ornithine improves athletic performance, has anabolic effects, has wound-healing effects, and is immuno-enhancing.

Aspatrend is also used to associated treatment for these conditions: Hepatic Encephalopathy (HE), Amino acid supplementation

How Aspatrend works

L-Aspatrend is metabolised to L-arginine. L-arginine stimulates the pituitary release of growth hormone. Burns or other injuries affect the state of L-arginine in tissues throughout the body. As De novo synthesis of L-arginine during these conditions is usually not sufficient for normal immune function, nor for normal protein synthesis, L-ornithine may have immunomodulatory and wound-healing activities under these conditions (by virtue of its metabolism to L-arginine).

Toxicity

Oral, rat LD50 = 10000 mg/kg

Food Interaction

No interactions found.

Elimination Route

Absorbed from the small intestine via a sodium-dependent active transport process

Innovators Monograph

You find simplified version here Aspatrend

http://classyfire.wishartlab.com/tax_nodes/C0000000
http://classyfire.wishartlab.com/tax_nodes/C0000264
http://classyfire.wishartlab.com/tax_nodes/C0000265
http://classyfire.wishartlab.com/tax_nodes/C0000013
http://classyfire.wishartlab.com/tax_nodes/C0004146
http://classyfire.wishartlab.com/tax_nodes/C0000262
http://classyfire.wishartlab.com/tax_nodes/C0004176
http://classyfire.wishartlab.com/tax_nodes/C0001137
http://classyfire.wishartlab.com/tax_nodes/C0001205
http://classyfire.wishartlab.com/tax_nodes/C0004557
http://classyfire.wishartlab.com/tax_nodes/C0003940
http://classyfire.wishartlab.com/tax_nodes/C0000469
http://classyfire.wishartlab.com/tax_nodes/C0004150
http://classyfire.wishartlab.com/tax_nodes/C0001831
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:15729
http://www.genome.jp/dbget-bin/www_bget?cpd:C00077
http://www.hmdb.ca/metabolites/HMDB0000214
http://www.genome.jp/dbget-bin/www_bget?cpd:C00077
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=6262
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46505239
https://www.chemspider.com/Chemical-Structure.6026.html
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487430
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=7704
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=15729
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL446143
https://zinc.docking.org/substances/ZINC000001532530
http://www.pharmgkb.org/drug/PA164783814
http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=725
https://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/ORN
http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/lor_0190.shtml
https://en.wikipedia.org/wiki/Ornithine
*** Taking medicines without doctor's advice can cause long-term problems.
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