A-Clam
A-Clam Uses, Dosage, Side Effects, Food Interaction and all others data.
A-Clam is a centrally acting muscle relaxant that acts at the reticular formation in the brain stem by blocking voltage-gated sodium and calcium channels
| Trade Name | A-Clam |
| Generic | Tolperisone |
| Tolperisone Other Names | Tolperisone |
| Weight | 50mg |
| Type | Tablet |
| Formula | C16H23NO |
| Weight | Average: 245.366 Monoisotopic: 245.177964365 |
| Groups | Investigational |
| Therapeutic Class | Central Depolarizing muscle relaxants, Centrally acting Skeletal Muscle Relaxants |
| Manufacturer | Acme Laboratories Limited |
| Available Country | Bangladesh |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Treatment of painful musculoskeletal disorders with hypermyotonia and decreased motility, especially those resulting from spinal cord injuries, osteoporosis, arthritis, and spasticity. It has also been effective in lumboischial pain, neurolathyrism, knee arthritis, peripheral circulatory diseases, climacteric muscular and vascular complaints, trismus, myogenous headaches, rheumatic diseases accompanied by muscular hypertonia, spasms, pain, inflammatory symptoms and limited motion, and in the post-surgical treatment of traumatologic patients.
A-Clam Hydrochloride is a centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. It effectively reduces muscular hypertonicity, improves peripheral blood flow by vasodilatation and reduces pain
A-Clam is also used to associated treatment for these conditions: Spasticity
Dosage
A-Clam dosage
Adult: 150-450 mg daily, administered in 2 or 3 divided doses. The maximum dosage is 450 mg/day.
Children:
- 3 months to 6 years: 1-2 mg/kg/day in 3 divided doses.
- 6 years to 14 years: 2-4 mg/kg/day in 3 divided doses
Side Effects
Diarrhea, dizziness, drowsiness, dryness of the mouth, fall of blood pressure, fatigue, gastric complaints, headaches, hypersensitivity, itching, muscle pain, muscle weakness, rash, and somnolence.
Precaution
In case of children, the prescribed dose and duration of treatment should closely be observed.
Interaction
Concomitant use of Methocarbamol with A-Clam Hydrochloride has been reported to cause disturbance of visual accommodation.
Pregnancy & Breastfeeding use
A-Clam Hydrochloride should be used in pregnancy according to physician's advice. A-Clam hydrochloride should not be used during breast-feeding.
Contraindication
Hypersensitivity, Myasthenia Gravis and nursing mother.
Acute Overdose
Excitability has been noted after ingestion of high doses by children. In suicide studies of three isolated cases, it is believed that ingestion of tolperisone was the cause of death.
Storage Condition
A-Clam Hydrochloride should be stored below 30° C. Keep out of reach of children
Innovators Monograph
You find simplified version here A-Clam
A-Clam contains Tolperisone see full prescribing information from innovator A-Clam Monograph, A-Clam MSDS, A-Clam FDA label
FAQ
What is A-Clam used for?
A-Clam is a muscle relaxant used to relieve spasticity after stroke in adults.A-Clam is an oral, centrally acting muscle relaxant.
How safe is A-Clam?
A-Clam hydrochloride represents an effective and safe treatment of central post stroke spasticity, neurolathyrism, and painful reflex muscle spasm without the typical side effects of centrally active muscle relaxants.
What are the common side effects of A-Clam?
The common side effects of A-Clam are include: tiredness, dizziness, nausea, mouth dryness, increase in liver enzymes. Contraindications: myasthenia gravis, pregnancy, breast feeding.
Is A-Clam safe during pregnancy?
A-Clam should be avoided, particularly during the first trimester of pregnancy to avoid embryo toxicity.
Is A-Clam safe during breastfeeding?
This medicine is not recommended for use in breastfeeding women since the safety and efficacy of use are not clinically established.
Can I drink alcohol with A-Clam?
A-Clam is not sedating and does not interact with alcohol.
How long does A-Clam take to work?
A-Clam is absorbed nearly completely from the gut and reaches its peak blood plasma concentration after 1.5 hours.
Is A-Clam a sedative?
A-Clam does not cause any sedation and does not impair reaction times.
How do you take A-Clam?
Take A-Clam with food.Take it with or after food or a glass of milk. Do not take in larger amounts than advised/prescribed.
Does A-Clam cause drowsiness?
The most common adverse effects were asthenia and sleepiness(drowsiness).
When should not I take A-Clam?
This medicine is not recommended for use in patients with a known allergy to A-Clam or any other inactive ingredient present along with it.
What happens if I miss a dose?
The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose.
What happens if I overdose?
Seek emergency medical treatment or contact the doctor in case of an overdose.
