A-Flox 250 mg Capsule

A-Flox 250 mg Capsule Uses, Dosage, Side Effects, Food Interaction and all others data.

Table Of contents

• A-Flox 250 mg Capsule
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	A-Flox 250 mg Capsule
Generic	Flucloxacillin Sodium
Weight	250 mg
Type	Capsule
Therapeutic Class	Penicillinase-resistant penicillins
Manufacturer	ACME Laboratories Ltd.
Available Country	Bangladesh
Last Updated:	September 24, 2024 at 5:38 am

Uses

Flucloxacillin is indicated for the treatment of infections due to Gram-positive organisms, including infections caused by penicillinase producing staphylococci. These indications include: Skin and soft tissue infections: Boils, abscess, carbuncles, infected skin conditions (e.g. ulcer, eczema, acne, furunculosis, cellulitis, infected wounds, infected burns, otitis media and externa, impetigo). ... Read more

Dosage

A-Flox 250 mg Capsule dosage

Oral administration: Adult: 250 mg four times daily. Dosage may be doubled in severe infections. In osteomyelitis and endocarditis, up to 8 gm daily is used in 6-8 hourly divided doses. Children (2-10 years): 1/2 of adult dose. Children (Under 2 years): 1/4 of adult dose. Parenteral administration:Adult or Elderly: Intramuscular Injection: 250 mg four times daily. Intravenous Injection: 250 mg-1 g four times daily by slow injection over 3 to 4 minutes or by intravenous infusion. All systemic doses may be doubled in severe infections: doses up to 8 g daily have been suggested for endocarditis or osteomyelitis. Children: 2-10 years: half of the adult dose. Under 2 years: a quarter of the adult dose. Oral doses should be administered 1 hour before meal.

Side Effects

There have been some common side effects of gastrointestinal tract such as nausea, vomiting, diarrhoea, dyspepsia and other minor gastrointestinal disturbances. Besides these rashes, urticaria, purpura, fever, interstitial nephritis, hepatitis and cholestatic jaundice have been reported.

Precaution

Flucloxacillin should be used with caution in patients with evidence of hepatic dysfunction. Caution should also be exercised in the treatment of patients with an allergic diathesis.

Interaction

Concurrent use of Flucloxacillin and may result in increased level of Flucloxacillin in blood for prolonged period.

Pregnancy & Breastfeeding use

US FDA Pregnancy Category of Flucloxacillin is B. There are, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Flucloxacillin have been shown to be excreted in human milk. So, caution should be exercised when Flucloxacillin is administered to a lactating mother.

Contraindication

Flucloxacillin is contraindicated in penicillin hypersensitive patients.

Special Warning

In severe renal failure (creatinine clearance <10 ml/min), a reduction in dose or an extension of dose interval should be considered.

Storage Condition

Keep in a dry place away from light and heat. Keep out of the reach of children.

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