Abafunginum

Abafunginum Uses, Dosage, Side Effects, Food Interaction and all others data.

Trade Name Abafunginum
Generic Abafungin
Abafungin Other Names Abafungin, Abafungina, Abafungine, Abafunginum
Type
Formula C21H22N4OS
Weight Average: 378.49
Monoisotopic: 378.151432518
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Abafunginum
Abafunginum

Uses

Investigated for use/treatment in fungal infections, bacterial infection, skin infections/disorders, and onychomycosis.

How Abafunginum works

Abafunginum has been shown to have fungicidal and fungistatic effects on a wide variety of pathogens, including dermatophytes, yeasts (Candida) and moulds. The drug acts on the infecting organisms in two ways: by interfering with the formation of a vital sterol in the fungal cell membrane, thereby preventing cell growth, and also by direct interaction with another membrane component resulting in membrane disruption, leakage of cellular contents and death of the cell and independent of whether it is in a non-metabolising (`resting') phase of development or actively growing. These features of abafungin, combined with the attainment of microbicidal concentrations in the skin from a 1% preparation, its long residence at the site of dermal application and the lack of significant systemic absorption, mean that Abasol(tm) is particularly attractive for the topical treatment of dermatomycoses, which is the first indication under review for marketing approval.

Innovators Monograph

You find simplified version here Abafunginum

*** Taking medicines without doctor's advice can cause long-term problems.
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