ABT-510
ABT-510 Uses, Dosage, Side Effects, Food Interaction and all others data.
ABT-510 is peptide mimetics of thrombospondin-1 (TSP-1), block angiogenesis in vitro and in vivo and slow tumor growth. It is developed by Abbott Laboratories for the treatment of Solid Tumors, Lymphoma and Melanoma.
Trade Name | ABT-510 |
Generic | ABT-510 |
Type | |
Formula | C46H83N13O11 |
Weight | Average: 994.2317 Monoisotopic: 993.633500563 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in lymphoma (unspecified), melanoma, and solid tumors.
How ABT-510 works
ABT-510 is a synthetic peptide that mimics the anti-angiogenic activity of the naturally occurring protein, thrombospondin-1 (TSP-1). Angiogenesis is the process of new blood vessel formation. ABT-510 blocks the actions of multiple pro-angiogenic growth factors known to play a role in cancer related blood vessel growth, such as VEGF, bFGF, HGF, and IL-8. ABT-510 is the first compound with this mechanism of action to be studied.
Innovators Monograph
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