Acnorm
Acnorm Uses, Dosage, Side Effects, Food Interaction and all others data.
Glycerin is a hyperosmotic laxative, given rectally, which usually produces a bowel movement within 15 minutes to 1 hour. Hyperosmotic laxatives encourage bowel movements by drawing water into the bowel from surrounding tissues. This produces a softer stool mass and increased bowel action. These products are used for fast, predictable relief of occasional constipation.
Glycerin is commonly classified as an osmotic laxative but may act additionally or alternatively through its local irritant effects; it may also have lubricating and fecal softening actions. Glycerin suppositories usually work within 15 to 30 minutes.
Zinc oxide is used to treat or prevent minor skin irritations such as burns, cuts, poison ivy, poison oak, poison sumac, and diaper rash. It is also used as a sunscreen.
Zinc oxide has astringent, soothing and protective properties and is used in topical preparations for eczema, slight excoriations, wounds and haemorrhoids. It also reflects ultraviolet radiation and can be used as a physical sunscreen.
| Trade Name | Acnorm |
| Generic | Sulfur + Glycerin + Calamine + Zinc Oxide |
| Weight | 3% |
| Type | Lotion |
| Therapeutic Class | |
| Manufacturer | Galcare Pharmaceutical Pvt Ltd |
| Available Country | India |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the relief of occasional constipation
Zinc Oxide helps to To treat or prevent skin irritations (e.g., burns, bed sore, cuts, poison ivy, diaper rash). Protects chafed skin due to diaper rash and helps seal out wetness.
Acnorm is also used to associated treatment for these conditions: Cold Sore, Constipation, Dry Mouth, Dry Skin, Dry throat, Edema of the cerebrum, Hypertension Intracranial, Occasional Constipation, Ocular Discomfort, Ocular Hypertension, Ocular Irritation, Skin Infections, Sore Throat, Mouth soreness, Ocular burning, Bowel preparation therapy, Topical Antisepsis, Skin protectionAcute Wounds, Burns first degree, Burns second degree, Dermatitis, Eczematous, Diaper Rash, Herpes Labialis, Injuries to the Nipple (Fissures and Cracks) Resulting Breastfeeding, Intertrigo, Pain, Pruritus, Sensitive Skin, Skin Irritation, Skin candida, Sunburn, Wounds, Chafing, Damaged skin, Dry, cracked skin, Facial rash, Heat rash, Superficial Wounds, Watery skin lesions, Astringent, Nutritional supplementation
How Acnorm works
When administered rectally, glycerin exerts a hygroscopic and/or local irritant action, drawing water from the tissues into the feces and reflexively stimulating evacuation. Glycerin decreases intraocular pressure by creating an osmotic gradient between the blood and intraocular fluid, causing fluid to move out of the aqueous and vitreous humors into the bloodstream.
It acts by providing a physical barrier to prevent skin irritation and help heal damaged skin.
Dosage
Acnorm dosage
Children under 2 years: Consult a physician.
Children (2 to 6 years): only 1 Glycerin 1.15 suppository per 24 hours or as directed by a physician.
Adults and Children (From 6 years): only 1 Glycerin 2.30 suppository per 24 hours or as directed by a physician
Insert suppository well up into rectum. Suppository need to melt completely to produce laxative action.
Apply thin layer topically every 8 hourly. Change wet and soiled diapers, promptly cleans the diaper area, allow to dry and apply ointment liberally as often as necessary, with each diaper change, especially at bedtime or any time when exposure to wet diapers may be prolonged.
Side Effects
Glycerin when used rectally may cause rectal discomfort or a burning sensation
Usually well tolerated. Extremely low frequency of hypersensitivity reaction.
Toxicity
Glycerol has very low toxicity when ingested ; Rat LD50 (oral)-12600mg/kg Mice LD50 (oral )-4090mg/kg Human TDLo (oral) - 1428mg/kg
Acute oral toxicity (LD50): 7950 mg/kg [Mouse].
Precaution
For external use only. Avoid contact with the eyes. Stop use and ask a doctor if condition worsens or does not improve within 7 days. Keep out of the reach of children. If swallowed, get medical help or contact a poison control center right away
Volume of Distribution
Glycerin is distributed throughout the blood. Although glycerin generally does not appear in ocular fluids, it may enter the orbital sac when the eye is inflamed, with a consequent decrease in osmotic effect.
Intended for local use only, no systemic absorption.
Elimination Route
Well absorbed orally, poorly absorbed rectally. Studies in humans and animals indicate glycerol is rapidly absorbed in the intestine and the stomach
No significant percutaneous absorption from topically applied zinc oxide.
Half Life
30 - 45 minutes
Intended for local use only, no systemic absorption.
Clearance
Intended for local use only, no systemic absorption.
Elimination Route
Approx 7-14% of dose is excreted unchanged in the urine within 2.5 hr.
Intended for local use only, no systemic absorption.
Pregnancy & Breastfeeding use
Pregnancy category C. There are no controlled data in human pregnancy
This medication should be used with precautions only if clearly needed during pregnancy or while breast feeding
Contraindication
Sensitivity to the ingredients. Do not use unless the patient to be treated is, in fact, constipated.
Known hypersensitivity to any component of the preparation
Acute Overdose
No overdose related problem is yet reported.
Storage Condition
Store below 25° C. Protect from moisture.
keep in a cool and dry place, away from light.
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