Afimoxifene

Afimoxifene Uses, Dosage, Side Effects, Food Interaction and all others data.

Afimoxifene (4-Hydroxytamoxifen, trade name TamoGel) is a new estrogen inhibitor under investigation for a variety of estrogen-dependent conditions, including cyclic breast pain and gynecomastia. TamoGel is formulated using Enhanced Hydroalcoholic Gel (EHG) Technology. This technology enables percutaneous delivery of drugs that cannot be delivered orally. It is being developed by Ascent Therapeutics.

Trade Name Afimoxifene
Generic Afimoxifene
Afimoxifene Other Names 4-hydroxytamoxifen, 4-monohydroxytamoxifen, 4-OHT, Afimoxifene
Type
Formula C26H29NO2
Weight Average: 387.514
Monoisotopic: 387.219829177
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Afimoxifene
Afimoxifene

Uses

For the potential treatment of menstrual-cycle related mastalgia, fibrocystic breast disease, breast disease, gynecomastia and Keloid scarring.

How Afimoxifene works

Afimoxifene binds to estrogen receptors (ER), inducing a conformational change in the receptor. This results in a blockage or change in the expression of estrogen dependent genes.

Elimination Route

Absorbed following topical application.

Innovators Monograph

You find simplified version here Afimoxifene

*** Taking medicines without doctor's advice can cause long-term problems.
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