Albucide Liqvo

Albucide Liqvo Uses, Dosage, Side Effects, Food Interaction and all others data.

Albucide Liqvo is a molecule containing the sulfonamide functional group attached to an aniline.

Albucide Liqvo is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Trade Name Albucide Liqvo
Generic Sulfanilamide
Sulfanilamide Other Names p-aminobenzenesulfamide, p-aminobenzenesulfonamide, para-aminobenzenesulfonamide, Prontosil album, Streptocide, Sulfamine, Sulfanilamida, Sulfanilamide, Sulfanilamidum, Sulphanilamide
Type
Formula C6H8N2O2S
Weight Average: 172.205
Monoisotopic: 172.0306482
Groups Approved
Therapeutic Class
Manufacturer
Available Country Georgia
Last Updated: September 19, 2023 at 7:00 am
Albucide Liqvo
Albucide Liqvo

Uses

Albucide Liqvo is a sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans.

For the treatment of vulvovaginitis caused by Candida albicans.

Albucide Liqvo is also used to associated treatment for these conditions: Vulvovaginal Candidiasis

How Albucide Liqvo works

Albucide Liqvo is a competitive inhibitor of bacterial enzyme dihydropteroate synthetase. This enzyme normally uses para-aminobenzoic acid (PABA) for synthesizing the necessary folic acid. The inhibited reaction is normally necessary in these organisms for the synthesis of folic acid. Without it, bacteria cannot replicate.

Toxicity

Oral, mouse LD50 = 3700 mg/kg; Intravenous, mouse LD50 = 621 mg/kg; Oral, rabbit LD50 = 1300 mg/kg. Side effects include itching, burning, skin rash, redness, swelling, or other sign of irritation not present before use of this medicine and long-term use of sulfonamides may cause cancer of the thyroid gland.

Food Interaction

No interactions found.

Elimination Route

Sulfonamides are absorbed through the vaginal mucosa. There are no pharmacokinetic data available describing how much of an intravaginal dose reaches the systemic circulation.

Innovators Monograph

You find simplified version here Albucide Liqvo

http://classyfire.wishartlab.com/tax_nodes/C0000000
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http://classyfire.wishartlab.com/tax_nodes/C0002279
http://classyfire.wishartlab.com/tax_nodes/C0000031
http://classyfire.wishartlab.com/tax_nodes/C0001925
http://classyfire.wishartlab.com/tax_nodes/C0004233
http://classyfire.wishartlab.com/tax_nodes/C0000284
http://classyfire.wishartlab.com/tax_nodes/C0001585
http://classyfire.wishartlab.com/tax_nodes/C0003137
http://classyfire.wishartlab.com/tax_nodes/C0002450
http://classyfire.wishartlab.com/tax_nodes/C0004557
http://classyfire.wishartlab.com/tax_nodes/C0003940
http://classyfire.wishartlab.com/tax_nodes/C0004150
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https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=10184
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=45373
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https://www.drugs.com/cdi/sulfanilamide.html
https://en.wikipedia.org/wiki/Sulfanilamide
*** Taking medicines without doctor's advice can cause long-term problems.
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