Aldonil

Aldonil Uses, Dosage, Side Effects, Food Interaction and all others data.

Aldonil is aldose reductase inhibitor. The aldose reductase inhibitors have a distinct mechanism of action, affecting the underlying disease process in diabetic neuropathy, although the extent of the polyol pathway involvement is yet to be determined. Aldonil reduces sorbitol accumulation in the sciatic nerve, erythrocytes. Aldonil may improve motor and sensory nerve conduction velocity and subjective neuropathy symptoms.

Table Of contents

• Aldonil
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Aldonil
Generic	Epalrestat
Epalrestat Other Names	Epalrestat
Type	Tablet
Formula	C15H13NO3S2
Weight	Average: 319.39 Monoisotopic: 319.033685631
Groups	Investigational
Therapeutic Class	Aldose reductase inhibitor
Manufacturer	Zydus Cadila Healthcare Ltd
Available Country	India
Last Updated:	September 19, 2023 at 7:00 am

Uses

Diabetic neuropathy

Dosage

Aldonil dosage

In general, for adults, take 1 tablet (50 mg of the active ingredient) at a time, three times daily, before meal. The dosage may be adjusted according to the age or symptoms.

Side Effects

The most commonly reported adverse reactions include abdominal pain, nausea, rash, itch, erythema and blister.

Precaution

Urine may turn yellowish brown or reddish after taking the medicine, because the yellowish brown or reddish color is attributed to components of this medicine.

Interaction

There are no known drug interactions and none well documented.

Pregnancy & Breastfeeding use

Pregnancy Category- Not Classified. FDA has not yet classified the drug into a specified pregnancy category

Contraindication

Hypersensitivity. Pregnant or breastfeeding.

Innovators Monograph

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