Aldoxorubicin Uses, Dosage, Side Effects and more
Aldoxorubicin, an antineoplastic agents, is an albumin-binding prodrug of doxorubicin.
| Trade Name | Aldoxorubicin |
| Generic | Aldoxorubicin |
| Aldoxorubicin Other Names | Aldoxorubicin |
| Type | |
| Formula | C37H42N4O13 |
| Weight | Average: 750.758 Monoisotopic: 750.274837428 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in solid tumors.
How Aldoxorubicin works
INNO-206 is the (6-Maleimidocaproyl) hydrazone of doxorubicin. INNO-206 is a prodrug of doxorubicin that binds endogenous albumin after administration. The bound doxorubicin is released in the acidic environment of the tumor cell through cleavage of an acid sensitive linker. In preclinical models, INNO-206 was superior to doxorubicin with regard to antitumor efficacy and toxicity.
