Aldoxorubicin

Aldoxorubicin Uses, Dosage, Side Effects, Food Interaction and all others data.

Aldoxorubicin, an antineoplastic agents, is an albumin-binding prodrug of doxorubicin.

Trade Name Aldoxorubicin
Generic Aldoxorubicin
Aldoxorubicin Other Names Aldoxorubicin
Type
Formula C37H42N4O13
Weight Average: 750.758
Monoisotopic: 750.274837428
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Aldoxorubicin
Aldoxorubicin

Uses

Investigated for use/treatment in solid tumors.

How Aldoxorubicin works

INNO-206 is the (6-Maleimidocaproyl) hydrazone of doxorubicin. INNO-206 is a prodrug of doxorubicin that binds endogenous albumin after administration. The bound doxorubicin is released in the acidic environment of the tumor cell through cleavage of an acid sensitive linker. In preclinical models, INNO-206 was superior to doxorubicin with regard to antitumor efficacy and toxicity.

Innovators Monograph

You find simplified version here Aldoxorubicin

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