Alimemazine Tartrate P & D
Alimemazine Tartrate P & D Uses, Dosage, Side Effects, Food Interaction and all others data.
A phenothiazine derivative that is used as an antipruritic.
Trimeprazine (also known as Alimemazine Tartrate P & D) is a tricyclic antihistamine, similar in structure to the phenothiazine antipsychotics, but differing in the ring-substitution and chain characteristics. Trimeprazine is in the same class of drugs as chlorpromazine (Thorazine) and trifluoperazine (Stelazine); however, unlike the other drugs in this class, trimeprazine is not used clinically as an anti-psychotic. It acts as an anti-histamine, a sedative, and an anti-emetic (anti-nausea). Trimeprazine is used principally as an anti-emetic, to prevent motion sickness or as an anti-histamine in combination with other medications in cough and cold preparations. Tricyclic antihistamines are also structurally-related to the tricyclic antidepressants, explaining the antihistaminergic adverse effects of these two drug classes and also the poor tolerability profile of tricyclic H1-antihistamines.
| Trade Name | Alimemazine Tartrate P & D |
| Generic | Alimemazine |
| Alimemazine Other Names | Alimemazina, Alimemazine, Alimemazinum, Methylpromazine, Trimeprazine |
| Type | |
| Formula | C18H22N2S |
| Weight | Average: 298.446 Monoisotopic: 298.150369404 |
| Groups | Approved, Vet approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | Malta |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Alimemazine Tartrate P & D is an antihistamine agent used to prevent and relieve allergic conditions which cause pruritus and other allergic skin conditions, including urticaria.
Used to prevent and relieve allergic conditions which cause pruritus (itching) and urticaria (some allergic skin reactions).
Alimemazine Tartrate P & D is also used to associated treatment for these conditions: Cough, Pruritus
How Alimemazine Tartrate P & D works
Trimeprazine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding.
Toxicity
Symptoms of overdose clumsiness or unsteadiness, seizures, severe drowsiness, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath, shuffling walk, tic-like (jerky) movements of head and face, trembling and shaking of hands, and insomnia.
Food Interaction
- Avoid alcohol. Ingesting alcohol may potentiate the CNS depressant effects of alimemazine/trimeprazine.
- Take after a meal. Taking alimemazine/trimeprazine after eating may reduce drowsiness by allowing for more gradual absorption.
Elimination Route
Well absorbed in the digestive tract.
Innovators Monograph
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