Alkof Am Cough
Alkof Am Cough Uses, Dosage, Side Effects, Food Interaction and all others data.
Alkof Am Cough is a metabolite of Bromhexine. It possesses mucokinetic (improvement in mucus transport) and secretolytic (liquefies secretions) properties. Alkof Am Cough stimulates the serous cells of the glands of the mucous membrane of bronchi, increasing the content of mucus secretion. The mucolytic effect is associated with depolymerization and splitting of mucoproteins and mucopolysaccharide fibres, which leads to reduction in the viscosity of mucus. Expectoration of mucus is facilitated and breathing is eased considerably. Alkof Am Cough stimulates production of phospholipids of surfactant by alveolar cells. Alkof Am Cough has anti-inflammatory properties. In patients with COPD, it improves airway patency. Beside these, Alkof Am Cough also exhibits anti-oxidant activity. Long-term use is possible because of the good tolerability of the preparation.
| Trade Name | Alkof Am Cough |
| Generic | Ambroxol |
| Ambroxol Other Names | Ambroxol, Ambroxolum, Bisolvon metabolite vIII, Bromhexine metabolite vIII, Bromhexine-metabolite vIII |
| Type | Syrup |
| Formula | C13H18Br2N2O |
| Weight | Average: 378.108 Monoisotopic: 375.978589 |
| Protein binding | Approximately 90% |
| Groups | Approved, Investigational |
| Therapeutic Class | Cough expectorants & mucolytics |
| Manufacturer | Alkem Laboratories Ltd |
| Available Country | India |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
- • Acute and chronic diseases of respiratory tracts associated with viscid mucus including acute and chronic bronchitis
- • Productive cough
- • Inflammatory diseases of Rhinopharyngeal tract (e.g. Laryngitis, Pharyngitis, Sinusitis and Rhinitis) associated with viscid mucus
- • Asthmatic bronchitis, Bronchial asthma with difficult departure of mucus
- • Bronchiectasis
- • Chronic pneumonia.
Alkof Am Cough is also used to associated treatment for these conditions: Airway secretion clearance therapy
How Alkof Am Cough works
Alkof Am Cough is a mucolytic agent. Excessive Nitric oxide (NO) is associated with inflammatory and some other disturbances of airways function. NO enhances the activation of soluble guanylate cyclase and cGMP accumulation. Alkof Am Cough has been shown to inhibit the NO-dependent activation of soluble guanylate cyclase. It is also possible that the inhibition of NO-dependent activation of soluble guanylate cyclase can suppress the excessive mucus secretion, therefore it lowers the phlegm viscosity and improves the mucociliary transport of bronchial secretions.
Dosage
Alkof Am Cough dosage
Average daily dose (preferably after meal):Pediatric Drops:
- 0-6 months: 0.5 ml 2 times a day
- 6-12 months: 1 ml 2 times a day
- 1-2 years: 1.25 ml 2 times a day
Syrup:
- 2-5 years: 2.5 ml (1/2 teaspoonful) 2-3 times a day
- 5-10 years: 5 ml (1 teaspoonful) 2-3 times a day
- 10 years and adults: 10 ml (2 teaspoonful) 3 times a day.
Sustained release capsule:
- Adult and children over 12 years old: 1 capsule once daily
Specific application features: Alkof Am Cough may be prescribed to patients suffering from diabetes mellitus.
Side Effects
Gastrointestinal side-effects like epigastric pain, gastric fullness may occur occasionally. Rarely allergic responses such as eruption, urticaria or angioneurotic edema may occur.
Precaution
Alkof Am Cough should be given cautiously to patients with gastric and duodenal ulceration or convulsive disorders. Patients with hepatic and renal insufficiency should take it with caution.
Interaction
Alkof Am Cough has no interaction with cardioactive glycosides, corticosteroids, bronchodilators, diuretics and antibiotics (normally used in the treatment of bronchopulmonary affections). But Alkof Am Cough should not be taken simultaneously with antitussives (e.g. Codeine) because mucus, which has been liquefied by Alkof Am Cough, might not be expectorated.
Elimination Route
Rapid and almost complete.
Half Life
7-12 hours
Pregnancy & Breastfeeding use
Pregnancy: Teratogenic and fetal toxicity studies have shown no harmful effect of Alkof Am Cough. However, it is advised not to use during pregnancy, especially in the 1st trimester.
Lactation: Safety during lactation has not been established.
Contraindication
Contraindicated in known hypersensitivity to Alkof Am Cough or Bromhexine.
Interaction with other Medicine
Alkof Am Cough has no interaction with cardioactive glycosides, corticosteroids, bronchodilators, diuretics and antibiotics (normally used in the treatment of bronchopulmonary affections). But Alkof Am Cough should not be taken simultaneously with antitussives (e.g. Codeine) because mucus, which has been liquefied by Alkof Am Cough, might not be expectorated.
Innovators Monograph
You find simplified version here Alkof Am Cough
Alkof Am Cough contains Ambroxol see full prescribing information from innovator Alkof Am Cough Monograph, Alkof Am Cough MSDS, Alkof Am Cough FDA label
FAQ
What is Alkof Am Cough used for?
Alkof Am Cough is used for conditions where there are a lot of thick mucus in the airway passages. Alkof Am Cough belongs to a group of medications called mucolytics.It is used in the treatment of respiratory diseases associated with viscid or excessive mucus.
How safe is Alkof Am Cough?
Alkof Am Cough is a safe and well-tolerated treatment of bronchopulmonary diseases with a well-balanced and favorable benefit-risk profile.
How does Alkof Am Cough work?
Alkof Am Cough works by thinning down the mucus in the airway passages, thus making the mucus less sticky and it also facilitates the removal of the mucus from the airways.
What are the common side effects of Alkof Am Cough?
Common side effects of Alkof Am Cough are include:
- Nausea
- Vomiting
- Diarrhea
- Gastrointestinal side effects
- Skin rash
- itching
- Infections
- Allergies
- Upset stomach
- Dizziness
- Weakness
- Dry mouth
- Indigestion
- Numbness in throat
- Numbness in mouth
- Taste disturbances
Is Alkof Am Cough safe during pregnancy?
Alkof Am Cough is not advisable to taken during the first trimester of pregnancy. Please seek your doctor's or pharmacist's advice before using Alkof Am Cough if you are pregnant.
Is Alkof Am Cough safe during breastfeeding?
As Alkof Am Cough is excreted in breast milk, it is not recommended to be taken while breastfeeding. Please seek your doctor's or pharmacist's advice before using this medication if you breastfeeding.
Can I drink alcohol with Alkof Am Cough?
No. Even though you can readily find products containing dextromethorphan OTC, these medicines can be very dangerous when mixed with alcohol.
Can I drive after taking Alkof Am Cough?
It is advisable not to drive any motor vehicle or operate heavy machinery as increased drowsiness and dizziness can occur after taking.
When should be taken of Alkof Am Cough?
The recommended dose is 30mg to be taken three times a day.
How long does Alkof Am Cough take to work?
When administered orally onset of action occurs after about 30 minutes.
How long should I take Alkof Am Cough?
Alkof Am Cough was administered intramuscularly daily for 6-10 days at the following dosages: 1.7 mg/kg (children <2 years), 1.6 mg/kg (children 2-5 years) and 1.2 mg/kg (6-10 years).
What happens if I miss a dose?
If you miss a dose, use this drug as soon as you find it. Skip the missed dose and restart your dosing schedule if it is close to the time of your next dose. Do not use an additional dose in order to make up for the missing dose.
What happens if I overdose of Alkof Am Cough?
Do not take more than the dosage given. Your symptoms will not be changed by taking more medication; they can instead cause poisoning or severe side effects. If you believe that you or someone else might have overdosed on Alkof Am Cough Hydrochloride Syrup, please go to the nearest hospital or nursing home emergency room.
Who should not take Alkof Am Cough?
If you have serious gastric ulceration, liver or kidney issues, notify your healthcare professionals. If you have a confirmed history of an allergy to Alkof Am Cough, or any of the other ingredients mentioned in the medicine, this drug should be avoided.
Can I take Alkof Am Cough on an empty stomach?
The tablets may be taken with or without food.
Is Alkof Am Cough for dry cough?
Alkof Am Cough is more effective in productive cough treatment associated with the formation of sticky and thick mucus in the airway passages and is difficult to clear.Alkof Am Cough reduces its thickness and makes its removal easier from the airways passage.
Is Alkof Am Cough good for itchy throat?
Alkof Am Cough has a beneficial pain-relieving effect in patients with acute sore throat, superior to that achieved by sucking a placebo lozenge.
Is Alkof Am Cough a steroid?
No, it is not an antibiotic or steroid; it belongs to a class of medicines called Expectorants or Mucolytics. It has no known effect against infections.
How often should I take Alkof Am Cough?
The recommended dose for adults is 1 tablet 3 times daily. For better effect, the patient may administer 2 tablets 2 times daily. The tablets should be taken with liquid.
Is Alkof Am Cough an antibiotic?
Alkof Am Cough is a mucolytic agent used in the treatment of respiratory diseases.
