Allergosan

Allergosan Uses, Dosage, Side Effects, Food Interaction and all others data.

Chlorpyramine is a first generation antihistamine used in Eastern European countries to treat bronchial asthma as well as allergice rhinitis, allergic conjunctivitis, and other allergic reactions. It is also indicated for Quincke's edema, allergic reactions to insect bites, food and drug allergies, and anaphylactic shock.

Chlorpyramine is a competitive reversible H1 receptor antagonist. This inhibits vasodilation, increases in vascular permeability, and tissue edema associated with histamine release. In addition, chloropyramine has some anticholinergic properties. These effects, along with its ability to pass through the blood-brain barrier lead to side effects such as drowsiness, weakness, vertigo, fatigue, dryness in the mouth, constipation, and rarely - visual disturbances and increase of intraocular pressure.

Trade Name Allergosan
Generic Chloropyramine
Chloropyramine Other Names Chloropyramine, Chloropyraminum, Chlorpyramine, Cloropiramina, Halopyramine
Type
Formula C16H20ClN3
Weight Average: 289.803
Monoisotopic: 289.134575362
Groups Experimental
Therapeutic Class
Manufacturer
Available Country Bulgaria, Georgia, Latvia
Last Updated: September 19, 2023 at 7:00 am
Allergosan
Allergosan

Uses

For the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions.

How Allergosan works

Allergosan binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine.

Toxicity

Oral (LD50): Acute: 142 mg/kg [Rat]. 135 mg/kg [Mouse]. DUST (LC50): Acute: 209 mg/m 2 hours [Rat].

Innovators Monograph

You find simplified version here Allergosan

*** Taking medicines without doctor's advice can cause long-term problems.
Share