Allogeneic Umbilical Cord Blood Derived Regulatory T-Cells
Allogeneic Umbilical Cord Blood Derived Regulatory T-Cells Uses, Dosage, Side Effects, Food Interaction and all others data.
Allogeneic Umbilical Cord Blood Derived Regulatory T-Cells is an off-the-shelf product composed of allogeneic umbilical cord blood derived regulatory T-cells (T-Reg cells), which can be used intravenously and without HLA matching. On the surface of these T-Reg cells, T-cell lung homing markers are expressed.
| Trade Name | Allogeneic Umbilical Cord Blood Derived Regulatory T-Cells |
| Generic | CK0802 |
| CK0802 Other Names | Allogeneic Umbilical Cord Blood Derived Regulatory T-Cells |
| Type | |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
How Allogeneic Umbilical Cord Blood Derived Regulatory T-Cells works
T-Reg cells engage with antigen-presenting cells lining the alveolar epithelium. This likely results in disarmament and dampening of the cytokine storm — seen with a study where there was a rapid decline in peripheral biomarkers and decreased blood levels of inflammatory cytokines after treatment with Allogeneic Umbilical Cord Blood Derived Regulatory T-Cells. It is also a possibility that these cells can calm inflammation where it is most active and act discriminately, avoiding general immunosuppression. This therapy is currently being investigated against COVID-19 acute respiratory distress syndrome (ARDS), inflammatory diseases, and autoimmune disorders.
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