Alpha-Narcotine
Alpha-Narcotine Uses, Dosage, Side Effects, Food Interaction and all others data.
Trade Name | Alpha-Narcotine |
Generic | Noscapine |
Noscapine Other Names | alpha-Narcotine, Noscapina, Noscapine, Noscapinum |
Type | |
Formula | C22H23NO7 |
Weight | Average: 413.4205 Monoisotopic: 413.147452095 |
Groups | Approved, Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Alpha-Narcotine is a non-sedating isoquinoline alkaloid used primarily for its antitussive properties.
Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma.
Alpha-Narcotine is also used to associated treatment for these conditions: Common Cold, Cough, Respiratory Diseases, Airway secretion clearance therapy
How Alpha-Narcotine works
Alpha-Narcotine's antitussive effects appear to be primarily mediated by its sigma receptor agonist activity. Evidence for this mechanism is suggested by experimental evidence in rats. Pretreatment with rimcazole, a sigma specific antagonist, causes a dose-dependent reduction in antitussive activity of noscapine.
Innovators Monograph
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