Alpha-Narcotine

Alpha-Narcotine Uses, Dosage, Side Effects, Food Interaction and all others data.

Trade Name Alpha-Narcotine
Generic Noscapine
Noscapine Other Names alpha-Narcotine, Noscapina, Noscapine, Noscapinum
Type
Formula C22H23NO7
Weight Average: 413.4205
Monoisotopic: 413.147452095
Groups Approved, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Alpha-Narcotine
Alpha-Narcotine

Uses

Alpha-Narcotine is a non-sedating isoquinoline alkaloid used primarily for its antitussive properties.

Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma.

Alpha-Narcotine is also used to associated treatment for these conditions: Common Cold, Cough, Respiratory Diseases, Airway secretion clearance therapy

How Alpha-Narcotine works

Alpha-Narcotine's antitussive effects appear to be primarily mediated by its sigma receptor agonist activity. Evidence for this mechanism is suggested by experimental evidence in rats. Pretreatment with rimcazole, a sigma specific antagonist, causes a dose-dependent reduction in antitussive activity of noscapine.

Innovators Monograph

You find simplified version here Alpha-Narcotine

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