Aluminum Hydroxide
Aluminum Hydroxide Uses, Dosage, Side Effects, Food Interaction and all others data.
Aluminum Hydroxide is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects.
Gastric-peptic disease occurs as a result of an imbalance between protective factors, such as mucus, bicarbonate, and prostaglandin secretion, and aggressive factors, such as hydrochloric acid, pepsin, and Helicobacter pylori (H. pylori). Antacids work by restoring acid-base balance, attenuating the pepsin activity and increasing bicarbonate and prostaglandin secretion.
Trade Name | Aluminum Hydroxide |
Generic | Aluminum hydroxide |
Aluminum hydroxide Other Names | Aluminio hidróxido, Aluminium hydroxide, Aluminum hydroxide, Aluminum hydroxide, dried, Dried aluminium hydroxide, Dried aluminum hydroxide gel |
Weight | 320mg/5ml, 200mg + 200mg + 20mg/5ml, 400mg + 400mg + 40mg/5ml, 200mg + 200mg + 25mg |
Type | Oral Suspension, Oral Tablet, Chewable |
Formula | AlH3O3 |
Weight | Average: 78.0036 Monoisotopic: 77.989757403 |
Groups | Approved, Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | United States |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Aluminum Hydroxide is an antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
For relief of heartburn and acid indigestion.
Aluminum Hydroxide is also used to associated treatment for these conditions: Abdominal Pain, Acid Reflux, Acid Regurgitation, Acid indigestion, Anginal Pain caused by Gas, Bloating, Colic, Duodenal Ulcer, Dyspepsia, Flatulence, Gastric Ulcer, Gastroesophageal Reflux, Heartburn, Hyperphosphataemia, Pain, Inflammatory, Skin Irritation, Upset stomach, Stomach pains caused by Gastric Acid, Gastric Acid Suppression
How Aluminum Hydroxide works
Aluminum Hydroxide is a basic inorganic salt that acts by neutralizing hydrochloric acid in gastric secretions. Aluminum Hydroxide is slowly solubilized in the stomach and reacts with hydrochloric acid to form aluminum chloride and water. It also inhibits the action of pepsin by increasing the pH and via adsorption. Cytoprotective effects may occur through increases in bicarbonate ion (HCO3-) and prostaglandins.
Food Interaction
- Avoid foods rich in citrate. Citrate may increase the absorption of aluminum and has the potential to cause toxicity.
Elimination Route
Approximately 17-30% of the aluminum chloride formed is absorbed.
Elimination Route
Absorbed aluminum chloride is rapidly eliminated by the kidneys in patients with normal renal function.
Innovators Monograph
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