AM103

AM103 Uses, Dosage, Side Effects, Food Interaction and all others data.

AM103 is a novel inhibitor of 5-lipoxygenase-activiting protein (FLAP) that has demonstrated potential to treat asthma and cardiovascular disease by preventing the synthesis of LT, which triggers inflammation. It is being developed by Amira.

Results from the Phase I trial show that AM103 is safe and well-tolerated at doses up to 1,000 mg per day with no evidence of significant side effects. Pharmacodynamic data demonstrated a robust and statistically significant reduction of LTB4 and LTE4 in a dose-dependent manner.

Trade Name AM103
Generic AM103
Type
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
AM103
AM103

Uses

For the treatment of asthma and cardiovascular disease.

How AM103 works

The exact mechanism of actions is not known, however, AM103 inhibits the 5-lipoxygenase-activiting protein (FLAP). This prevents the synthesis of LT, which normally triggers inflammation.

Elimination Route

Well absorbed orally.

Innovators Monograph

You find simplified version here AM103

*** Taking medicines without doctor's advice can cause long-term problems.
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