Ambuterol Oral Solution 5 mg/5 ml
Ambuterol Oral Solution 5 mg/5 ml Uses, Dosage, Side Effects, Food Interaction and all others data.
| Trade Name | Ambuterol Oral Solution 5 mg/5 ml |
| Generic | Bambuterol Hydrochloride |
| Weight | 5 mg/5 ml |
| Type | Oral Solution |
| Therapeutic Class | Short-acting selective & β2-adrenoceptor stimulants |
| Manufacturer | APC Pharma Ltd. |
| Available Country | Bangladesh |
| Last Updated: | October 19, 2023 at 6:27 am |
Uses
Bambuterol is indicated for Bronchial asthma, Chronic bronchitis, Emphysema & Other lung diseases where bronchospasm is a complicating factor.Dosage
Ambuterol Oral Solution 5 mg/5 ml dosage
Children 2-5 years: The recommended normal dose 10 mg (10 ml syrup).Children 6-12 years: The recommended normal dose 10 mg (10 ml syrup). The dose may be increased to 20 mg.Adult: The recommended initial dose 10 mg. The dose may be increased to 20 mg after 1-2 weeks depending on the clinical effect.Side Effects
Fatigue, nausea, palpitation, headache, dizziness & tremor.Precaution
Dose should be reduced in patients with severely impaired renal function, patiensts with genetic deficiencies of plasma cholineterase, patient with severe ischemic heart disease.Interaction
Succinylcholin, MAOIs (monoamine oxidase inhibitors), ß2-blockers, corticosteroids, diuretics, muscle relaxants, sympathomimetic xanthine derivatives.Pregnancy & Breastfeeding use
Although no teratogenic effects have been observed in animal after administration of bambuterol, caution is recommended during first trimester of pregnancy. It is not known whether bambuterol or intermediary metabolites pass over to breast milk, so caution is recommended if bambuterol is administered to patients who are breast feeding. Terbutalin passes over to breast milk but an influence on the child is unlikely with therapeutic doses. Transient hypoglycemia has been reported in new born pre-term infants after maternal ß2 agonist treatment.Contraindication
Hepatic impairment, liver cirrhosis or severely impaired liver function.Acute Overdose
No case of bambuterol overdosage has yet been reported in human. It is likely that overdosing would result in high levels of terbutaline & therefore the same symptoms & signs may include: headache, anxiety, tremor, nausea, tonic muscle cramps, palpitations, tachycardia & cardiac arrythmias. A fall in blood pressure sometimes occurs after terbutaline overdosage. Laboratory findings: hyperglycaemia and lactacidosis sometimes occur. High doses of ß2-agonists maycause hypokalemia as a result of redistribution of potassium.Storage Condition
Keep away from light, store in a cool and dry place. Keep out of reach of children.Innovators Monograph
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