Ametazole

Ametazole Uses, Dosage, Side Effects, Food Interaction and all others data.

A histamine H2 agonist used clinically to test gastric secretory function.

Ametazole is a histamine H2 agonist used in a test for measuring maximal production of gastric acidity or anacidity. This measurement can be used to diagnose diseases such as Zollinger-Ellison syndrome, whereby the volume of gastric and basal secretions is measured following betazole administration (greater than 60% of the maximal acid secretion following betazole stimulation). In another test, gastritis can be diagnosed given late absence of gastric acid which is unresponsive to betazole stimulation. Ametazole can be used as a gastric secretory stimulant instead of histamine with the advantage of not provoking side effects and thus not requiring the use of antihistaminic compounds.

Trade Name Ametazole
Generic Betazole
Betazole Other Names Ametazole, Betazol, Betazole, Betazolum
Type
Formula C5H9N3
Weight Average: 111.1451
Monoisotopic: 111.079647303
Protein binding

> 99%

Groups Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Ametazole
Ametazole

Uses

For use clinically to test gastric secretory function.

How Ametazole works

Ametazole is a histamine analogue. It produces the same effects as histamine, binding the H2 receptor which is a mediator of gastric acid secretion. This agonist action thereby results in an increase in the volume of gastric acid produced.

Elimination Route

Rapid and complete.

Innovators Monograph

You find simplified version here Ametazole

*** Taking medicines without doctor's advice can cause long-term problems.
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