Ametazole
Ametazole Uses, Dosage, Side Effects, Food Interaction and all others data.
A histamine H2 agonist used clinically to test gastric secretory function.
Ametazole is a histamine H2 agonist used in a test for measuring maximal production of gastric acidity or anacidity. This measurement can be used to diagnose diseases such as Zollinger-Ellison syndrome, whereby the volume of gastric and basal secretions is measured following betazole administration (greater than 60% of the maximal acid secretion following betazole stimulation). In another test, gastritis can be diagnosed given late absence of gastric acid which is unresponsive to betazole stimulation. Ametazole can be used as a gastric secretory stimulant instead of histamine with the advantage of not provoking side effects and thus not requiring the use of antihistaminic compounds.
| Trade Name | Ametazole |
| Generic | Betazole |
| Betazole Other Names | Ametazole, Betazol, Betazole, Betazolum |
| Type | |
| Formula | C5H9N3 |
| Weight | Average: 111.1451 Monoisotopic: 111.079647303 |
| Protein binding | > 99% |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
For use clinically to test gastric secretory function.
How Ametazole works
Ametazole is a histamine analogue. It produces the same effects as histamine, binding the H2 receptor which is a mediator of gastric acid secretion. This agonist action thereby results in an increase in the volume of gastric acid produced.
Elimination Route
Rapid and complete.
Innovators Monograph
You find simplified version here Ametazole
