AmiClean 15 mg Tablet

AmiClean 15 mg Tablet Uses, Dosage, Side Effects, Food Interaction and all others data.

Sodium thiosulfate acts as an antidote in the treatment of cyanide poisoning. It acts as a sulphur-donating substrate for the enzyme rhodanese, thus speeding up the conversion of cyanide to thiocyanide, which is relatively non toxic. It is often used in combination with sodium nitrite but may be used alone in less severe poisoning.

AmiClean 15 mg Tablet
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	AmiClean 15 mg Tablet
Generic	Sodium Thiosulfate
Weight	15 mg
Type	Tablet
Therapeutic Class	Antidote preparations
Manufacturer	Amico Laboratories Ltd.
Available Country	Bangladesh
Last Updated:	September 24, 2024 at 5:38 am

Uses

Cyanide poisoning

Dosage

AmiClean 15 mg Tablet dosage

Adult: To be given after 300 mg of sodium nitrite has been admin over 5-20 min: 12.5 g of sodium thiosulfate (50 ml of a 25% solution or 25 ml of a 50% solution) given over 10 min. Methaemoglobin concentration should not exceed 30-40%. If symptoms of cyanide toxicity recur, the doses of nitrite and thiosulfate may be repeated after 30 min at half the initial doses.

Child: To be given after 4-10 mg/kg of sodium nitrite (max: 300 mg) has been admin: 400 mg/kg of sodium thiosulfate, as a 25 or 50% solution (max: 12.5 g). Methaemoglobin concentration should not exceed 30-40%. If symptoms of cyanide toxicity recur, the doses of nitrite and thiosulfate may be repeated after 30 min at half the initial doses.

Side Effects

Osmotic disturbances. Oral: catharsis (at high doses).

Precaution

May irritate eyes, skin and respiratory tract.

Interaction

Decreases toxicity of cisplatin through rapid chemical inactivation of its platinum component.

Pregnancy & Breastfeeding use

Pregnancy Category- C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Contraindication

Oedematous sodium-retaining conditions.

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FAQ

What is AmiClean 15 mg Tablet used for?

AmiClean 15 mg Tablet used as a medication to treat cyanide poisoning, pityriasis versicolor, and to decrease side effects from cisplatin. For cyanide poisoning it is often used after the medication sodium nitrite and typically only recommended for severe cases.

How safe is AmiClean 15 mg Tablet?

Ingestion of large amounts may cause gastrointestinal irritation.May cause respiratory tract irritation. Low hazard for usual industrial handling.

How does AmiClean 15 mg Tablet work?

AmiClean 15 mg Tablet works by helping cells in the body convert cyanide to a form that can be removed from the body through urination.

What are the common side effects of AmiClean 15 mg Tablet?

Common side effects of AmiClean 15 mg Tablet are include:

Agitation.
hallucinations (seeing, hearing, or feeling things that are not there)
mental changes.
muscle cramps.
nausea and vomiting.
pain in the joints.
ringing in the ears.

Is AmiClean 15 mg Tablet safe during pregnancy?

If AmiClean 15 mg Tablet is required in the management of cyanide poisoning during pregnancy, treatment should not be withheld on account of pregnancy.

Is AmiClean 15 mg Tablet safe during breastfeeding?

Breastfeeding is not recommended.There is no information regarding this drug on the presence in human milk, the effects on a breastfed infant, or effects on milk production.

What happens if I ingest AmiClean 15 mg Tablet?

light-headed feeling, like you might pass out, shortness of breath, tiredness; fast or irregular heart rate, pounding heartbeats or fluttering in your chest.

What does AmiClean 15 mg Tablet do to the body?

AmiClean 15 mg Tablet works by helping cells in the body convert cyanide to a form that can be removed from the body through urination.

How quickly does AmiClean 15 mg Tablet work?

Symptomatic relief and clinical improvement may occur within 2 weeks.

Is AmiClean 15 mg Tablet good for skin?

AmiClean 15 mg Tablet is used to treat a fungal infection of the skin called tinea versicolor.

Is AmiClean 15 mg Tablet bad for my skin?

Do not put on irritated skin. If you use AmiClean 15 mg Tablet and salicylic acid too often, your skin problem may become worse. Talk with your doctor before you use other drugs or products on your skin.

Does AmiClean 15 mg Tablet lower blood pressure?

AmiClean 15 mg Tablet can causes Low blood pressure also with other side effects.

When do I administer AmiClean 15 mg Tablet?

AmiClean 15 mg Tablet may be administered soon after prior treatment with a fast-acting cyanide antidote such as AmiClean 15 mg Tablet. Blood pressure must be monitored during infusion in both adults and children. The rate of infusion should be decreased if significant hypotension is noted.

Is AmiClean 15 mg Tablet light sensitive?

None under normal processing. Chemical Stable under normal conditions. Light sensitive.

Is AmiClean 15 mg Tablet a salicylic acid?

AmiClean 15 mg Tablet is an antifungal medicine that fights infections caused by fungus. salicylic acid helps your skin absorb the sodium thiosulfate.

Is AmiClean 15 mg Tablet a chemical antidote?

AmiClean 15 mg Tablet can be used for treatment of acute cyanide poisoning in combination with sodium nitrite.

How long is AmiClean 15 mg Tablet good for?

At the time of the case report, 18 months had elapsed since the infusions were discontinued, and the patient remained free of skin lesions. Based on the lack of recurrence with extended treatment, the authors suggested that the optimal duration of AmiClean 15 mg Tablet therapy is several months.

Is AmiClean 15 mg Tablet harmful to fish?

Excess AmiClean 15 mg Tablet up to 100 parts per million will not harm fish.

How quickly does AmiClean 15 mg Tablet work?

Symptomatic relief and clinical improvement may occur within 2 weeks.

Does AmiClean 15 mg Tablet remove oxygen?

AmiClean 15 mg Tablet acts as an oxygen scavenger. Oxygen scavengers are reducing agents in that they remove dissolved oxygen from water by reducing molecular oxygen to compounds in which oxygen appears in the lower.

Can I overdose AmiClean 15 mg Tablet?

AmiClean 15 mg Tablet is used to treat cyanide poisoning. If a poisoning or overdose occurs, get emergency help. Do not treat a poisoning or overdose yourself.