Amtri

Amtri Uses, Dosage, Side Effects, Food Interaction and all others data.

Amtri is an inorganic compound that is used as an antacid in the treatment of peptic ulcers.

Amtri works by increasing the pH of gastric juice via a neutralisation reaction. It also precipitates colloidal silica, which can coat gastrointestinal mucosa conferring further protection.

Table Of contents

• Amtri
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Amtri
Generic	Magnesium trisilicate
Magnesium trisilicate Other Names	Magnesio trisilicato
Weight	500mg
Type	Tablet
Formula	Mg2O8Si3
Weight	Average: 260.857 Monoisotopic: 259.86017997
Protein binding	33%
Groups	Approved
Therapeutic Class
Manufacturer	Mian Brothers Laboratories (pvt) Ltd,
Available Country	Pakistan
Last Updated:	September 19, 2023 at 7:00 am

Uses

Amtri is an antacid used for the symptomatic treatment of peptic ulcers.

For the treatment of peptic ulcers. Relieving indigestion and heartburn.

Amtri is also used to associated treatment for these conditions: Acid Reflux, Acid indigestion, Bloating, Colic, Flatulence, Gastric Ulcer, Heartburn, Upset stomach

How Amtri works

The gelatinous silicon dioxide, formed by the reaction of magnesium trisilicate with gastric contents is said to protect ulcerated mucosal surfaces and favor healing.

Toxicity

Adequate doses of magnesium trisilicate may cause diarrhea due to the action of soluble magnesium salts in the enteric tract. Approx 5% of the magnesium is absorbed.

Food Interaction

No interactions found.

Volume of Distribution

The hydrated silicon dioxide formed in the stomach and passes into the intestinal track.

Elimination Route

The hydrated silicon dioxide formed in the stomach and passes into the intestinal track where, silica can be partly absorbed.

Half Life

16-20 hours

Clearance

Maximum magnesium clearance is directly proportional to creatinine clearance.

Elimination Route

Excreted in the urine.

Innovators Monograph

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