Amylmetacresol

Amylmetacresol Uses, Dosage, Side Effects, Food Interaction and all others data.

Amylmetacresol is an antiseptic available in Canada over-the-counter in a number of lozenges for the treatment of sore throat and minor mouth infections , . Amylmetacresol is often combined with dichlorobenzyl alcohol and menthol in the commonly used sore throat lozenges, known as Strepsils .

The acute sore throat (pharyngitis) is one of the most common conditions for which children are seen in the primary care setting. Pharyngitis is normally caused by viruses and proves benign and self-limiting. Clinically proven, over-the-counter throat lozenges offer rapid and effective relief of acute sore throat symptoms, and are increasingly important in the management of this condition .

The mixture of amylmetacresol throat lozenge medications markedly reduces the infectivity of certain infectious viruses in the throat and in cough droplets, thus reducing opportunities for person-to-person transmission . In addition, it relieves symptoms of sore throat/irritation of the throat , .

Trade Name Amylmetacresol
Generic Amylmetacresol
Amylmetacresol Other Names amilmetacresol, Amyl metacresol, Amylmetacresol, amylmetacresolum
Type
Formula C12H18O
Weight Average: 178.275
Monoisotopic: 178.1357652
Groups Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Amylmetacresol
Amylmetacresol

Uses

Amylmetacresol is an antiseptic used to treat infections in the mouth and throat.

Sore throat, minor mouth and throat infections , , .

Amylmetacresol is also used to associated treatment for these conditions: Canker sores oral, Gingivitis, Inflammatory Disease of the Oral Cavity, Inflammatory Disease of the throat, Laryngitis, Orofacial Pain, Pharyngitis, Sore Throat, Stomatitis, Mouth infection, Mouth soreness, Pain in throat, Sore throat and hoarseness, Throat infections, Oral antisepsis

How Amylmetacresol works

The mechanism of virucidal action is not fully elucidated, however it is suggested that denaturation of external protein spikes, a pH-induced rearrangement of the tertiary structure of attachment proteins, or a selective effect on viral lipid membranes/protein–lipid interaction is responsible for this action .

Amylmetacresol is an antibacterial and antiviral agent, and blocks voltage-gated Na channels in a local anesthetic-like manner .

Toxicity

Oral LD50: 1500 mg/kg (rat)

Adverse effects include hypersensitivity reactions, tongue soreness .

Occasionally, hypersensitivity reactions may occur, manifested by digestive problems such as nausea or dyspepsia. This is extremely rare .

In the case of overdose, management should be symptomatic. In cases of severe overdosage, gastric lavage may be warranted to empty the stomach contents. Saline laxatives and activated charcoal may be administered orally .

Food Interaction

No interactions found.

Elimination Route

Rapidly absorbed and eliminated .

Innovators Monograph

You find simplified version here Amylmetacresol

*** Taking medicines without doctor's advice can cause long-term problems.
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