Antazol Plus
Antazol Plus Uses, Dosage, Side Effects, Food Interaction and all others data.
Xylometazoline Hydrochloride is a sympathomimetic agent with alpha-adrenergic activity. It produces vasoconstriction thus reducing nasal congestion. This enables patients suffering from colds to breathe more easily through the nose.
Sodium Cromoglicate usually acts through a local effect on the nasal mucosa. It prevents release of the mediators of type-l allergic reactions, including histamine and slow reacting substance of anaphylaxis (SRS-A) from sensitized mast cells after the antigen-antibody union has taken place. The drug does not inhibit the binding of IgE and the specific antigen; instead it suppresses the release of substances (e.g., histamine, SRS-A) in response to this reaction. The drug also inhibits Type-III (late allergic, Arthers) reactions to a lesser extent.
| Trade Name | Antazol Plus |
| Generic | Sodium Cromoglicate + Xylometazoline Hydrochloride |
| Weight | (2.6mg+0325mg)/actuation |
| Type | Nasal Spray |
| Therapeutic Class | Mast Cell Stabiliser |
| Manufacturer | Square Pharmaceuticals Ltd |
| Available Country | Bangladesh |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
This Nasal Spray is used for the prophylaxis and treatment of allergic rhinitis (such as hay fever and perennial rhinitis) where this is accompanied by nasal congestion.
Dosage
Antazol Plus dosage
Adults (including the elderly) and children: One spray each nostril four times daily.
Side Effects
No serious side effects have been reported. Occasional irritation of the nasal mucosa may occur during the first day of use. In rare cases with Sodium Cromoglicate solutions alone wheezing and tightness of the chest has been reported. Because a lower dose of Xylometazoline is employed in Antazol Plus it causes mild side effects such as nasal irritation, dryness of the nose, sneezing, headache, insomnia, drowsiness and palpitations.
Precaution
The prolonged use or abuse of decongestants in general may lead to rebound congestion or drug induced rhinitis.
Interaction
No evidence of interaction with other drugs has been observed.
Pregnancy & Breastfeeding use
As with all medicines, caution should be exercised during pregnancy especially during the first trimester.
Contraindication
Contraindicated in patients with a known hypersensitivity to any ingredients of the preparation.
Acute Overdose
Overdose is unlikely. In the event of accidental ingestion, symptomatic treatment is recommended.
Storage Condition
Store at a temperature not exceeding 30° C. Protect from light & moisture. Keep out of reach of children.
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