Anti-Angin Formula

Uses

Tetracaine is a local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures.

Ophthalmic tetracaine is indicated for the for procedures requiring a rapid and short- acting topical ophthalmic anesthetic.

The combination lidocaine and tetracaine patch is indicated for local dermal analgesia for superficial dermatological procedures and superficial venous access. The combination lidocaine and tetracaine cream is intended to provide topical local analgesia for superficial dermatological procedures.

Anti-Angin Formula is also used to associated treatment for these conditions: Common Cold, Cough, Fever, Flu caused by Influenza, Hoarseness, Pain, Throat irritation, Airway secretion clearance therapy, Nutritional supplementation, Vitamin supplementationDermabrasion, Hemorrhoids, Insect Bites, Rash caused by poison ivy, Sunburn, Minor burns, Anesthetics, Local, Local Anesthesia of the Skin, Local anesthesia therapy

How Anti-Angin Formula works

Tetracaine is an ester-type anesthetic and produces local anesthesia by blocking the sodium ion channels involved in initiation and conduction of neuronal impulses.

Toxicity

The most common adverse effects with the combination cream are localized reactions such as: erythema (47%), skin discoloration (16%), and edema (14%). Systemic adverse events were less common, occurring at a rate of <1% and included vomiting, headache, dizziness, and fever. Similar to other amide and ester anesthetics, CNS excitation and/or depression may occur. It is not well known at which plasma concentration systemic toxicity occurs with tetracaine; however, the threshold is thought to be much lower than that of lidocaine which is 1000 ng/mL.

Volume of Distribution

Tetracaine is rapidly hydrolyzed in the plasma; therefore, volume of distribution could not be determined.

Elimination Route

Systemic absorption of anaesthetic from the combination cream is directly related to the duration and surface area of application. Although peak plasma concentrations for lidocaine were measured, plasma levels for tetracaine could not be determined due to low levels (<0.9 ng/mL)

Half Life

Tetracaine is hydrolyzed rapidly in the plasma; therefore, half-life has not been determined.

Clearance

Tetracaine is hydrolyzed rapidly in the plasma; therefore, clearance has not been determined.

Innovators Monograph

You find simplified version here Anti-Angin Formula