Apatorsen
Apatorsen Uses, Dosage, Side Effects, Food Interaction and all others data.
Apatorsen is a second generation antisense drug which in preclinical experiments, inhibits production of Heat Shock Protein 27 (Hsp27) a cell survival protein found at elevated levels in many human cancers including prostate, lung, breast, ovarian, bladder, renal, pancreatic, multiple myeloma and liver cancer.
OGX-427 significantly decreases levels of Hsp27, induces apoptosis in several human cancer cell lines, has single agent anti-tumor activity, and acts as a chemosensitizer in combination with several cytotoxic drugs including docetaxel.
Trade Name | Apatorsen |
Generic | Apatorsen |
Apatorsen Other Names | Apatorsen |
Type | |
Formula | C224H304N79O116P19S19 |
Weight | Average: 7156.97 Monoisotopic: 7152.002582293 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in cancer/tumors (unspecified).
Innovators Monograph
You find simplified version here Apatorsen