Apatorsen Uses, Dosage, Side Effects and more
Apatorsen is a second generation antisense drug which in preclinical experiments, inhibits production of Heat Shock Protein 27 (Hsp27) a cell survival protein found at elevated levels in many human cancers including prostate, lung, breast, ovarian, bladder, renal, pancreatic, multiple myeloma and liver cancer.
OGX-427 significantly decreases levels of Hsp27, induces apoptosis in several human cancer cell lines, has single agent anti-tumor activity, and acts as a chemosensitizer in combination with several cytotoxic drugs including docetaxel.
| Trade Name | Apatorsen |
| Generic | Apatorsen |
| Apatorsen Other Names | Apatorsen |
| Type | |
| Formula | C224H304N79O116P19S19 |
| Weight | Average: 7156.97 Monoisotopic: 7152.002582293 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in cancer/tumors (unspecified).
