Aragan Plus
Aragan Plus Uses, Dosage, Side Effects, Food Interaction and all others data.
Sodium hyaluronate is a polysaccharide which functions as a tissue lubricant. It is widely used in ophthalmic surgery because it forms a viscoelastic solution in water which makes it a suitable substitute for aqueous and vitreous humour.
| Trade Name | Aragan Plus |
| Generic | Sodium Hyaluronate |
| Type | |
| Therapeutic Class | Drugs for Osteoarthritis |
| Manufacturer | |
| Available Country | Malaysia |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Aragan Plus is used for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy, and to simple analgesics, e.g., acetaminophen.
Aragan Plus is a viscous solution consisting of a high molecular weight fraction of purified natural sodium hyaluronate in buffered physiological sodium phosphate. It has a pH of 5.5-7.0. Hyaluronic acid is an important component of the body's extracellular matrix and is present in a particularly high concentration in cartilage and synovial fluid. Endogenous hyaluronic acid provides viscosity and elasticity to synovial fluid, which is fundamental for its lubricating and shock absorbing properties. It is essential for the correct structure of proteoglycans in articular cartilage. In osteoarthritis there is an insufficient amount of and a chance in the quality of hyaluronic acid in synovial fluid and cartilage. The intra-articular administration of hyaluronic acid into arthritic joints with degenerating cartilage surfaces and pathologically altered synovial fluid improved functions.
Dosage
Aragan Plus dosage
Aragan Plus is administered by intra-articular injection. A treatment cycle consists of five injections given at weekly intervals. Some patients may experience benefit with three injections given at weekly intervals. Inject the full 2 ml in one knee only. If treatment is bilateral, a separate injection should be used for each knee.
Side Effects
The common side-effects include gastrointestinal complaints, injection site pain, knee swelling/effusion, local skin reactions (rash, ecchymosis), pruritus, and headache.
Precaution
Use caution when injecting Aragan Plus into patients who are allergic to avian proteins, feathers, and egg products. Strict aseptic administration technique must be followed. Remove joint effusion, if present, before injecting Aragan Plus. Do not use the same syringe for removing joint effusion and for injecting Aragan Plus. It is recommended that the patient avoid any strenuous activities or prolonged (i.e., more than 1 hour) weight-bearing activities such as jogging or tennis within 48 hours following the intra-articular injection.
Pregnancy & Breastfeeding use
The safety and effectiveness of Aragan Plus have not been established in pregnant women. It is not known if Aragan Plus is excreted in human milk. The safety and effectiveness of Aragan Plus have not been established in lactating mother. The safety and effectiveness of Aragan Plus have not been demonstrated in children.
Contraindication
The drug is contraindicated in patients with known hypersensitivity to hyaluronate preparations. Intra-articular injections are contraindicated in cases of past and present infections or skin diseases in the area of the injection site.
Acute Overdose
No case of over dosage has been reported to date.
Storage Condition
Hyronate injection should be stored in a cool (below 25° C) and dry place and protected from light. Protect from freezing.
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FAQ
What is Aragan Plus used for?
Aragan Plus topical skin medication is used to treat skin ulcers such as bed sores or diabetic foot ulcers, as well as burn wounds, surgical incisions, cuts, abrasions, and other skin irritations. Aragan Plus skin medication is also used to treat dry or scaly skin.
How safe is Aragan Plus?
Aragan Plus as well as are considered safe. It's rarely associated with side effects when applied topically.
How does Aragan Plus work?
Aragan Plus works by pulling in moisture from the environment and the underlying layers of your skin into the epidermis.
What are the common side effects of Aragan Plus?
The common side effects of Aragan Plus are include:
- warmth, pain, redness, stiffness, bruising, or puffiness where the medicine was injected;
- nausea, stomach pain;
- trouble walking;
- swelling in your hands or feet;
- back pain, joint pain, muscle pain;
- numbness or tingly feeling;
- headache, dizziness; or
- runny or stuffy nose, sneezing, sore throat.
How is Aragan Plus given?
Aragan Plus is injected directly into your knee joint. A healthcare provider will give you this injection.
Aragan Plus is usually given once every week for 3 to 5 weeks. Follow your doctor's dosing instructions very carefully.
Who should not take Aragan Plus?
You should not receive a Aragan Plus injection if you have an infection in your knee or in the skin around your knee.
Is Aragan Plus safe during pregnancy?
Aragan Plus also safe to use during pregnant.
Is Aragan Plus safe during breastfeeding?
It is not known whether Aragan Plus topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Is Aragan Plus safe for skin?
Aragan Plus are considered safe. It's rarely associated with side effects when applied topically.
How long take Aragan Plus?
Aragan Plus usually given once every week for 3 to 5 weeks.
How long does Aragan Plus last?
Aragan Plus lasts for about six months or longer in most people.
How much Aragan Plus should I take?
Doses of 120–240 mg per day for at least one month have been shown to significantly increase skin moisture and reduce dry skin in adults.
Does Aragan Plus have long term benefits?
Studies show that long term use is safe, with no reported side effects from Aragan Plus supplementation. Used as a topical skincare ingredient, Aragan Plus is also well tolerated.
Is it OK to use Aragan Plus every day?
Yes, you can even use it twice a day as long as you're applying it to clean, damp skin, then locking it in with a moisturizer and face oil.
What happens if you use too much Aragan Plus?
Too much Aragan Plus can leave skin thirstier, and dehydration lines more prominent.
Does Aragan Plus lighten dark spots?
Aragan Plus can also minimize age spots and prevent any dark spots in the future on your skin.
Can Aragan Plus dry skin?
Aragan Plus is one of the most hydrating ingredients, but if misused,Aragan Plus can actually dry out your skin.
Is Aragan Plus good for pimples?
While Aragan Plus can't fill in visible acne scars, it can help reduce redness and the visible appearance of acne.
Is Aragan Plus good for wrinkles?
Aragan Plus is well known for its skin benefits, especially alleviating dry skin, reducing the appearance of fine lines and wrinkles and speeding up wound healing.
Is Aragan Plus good for hair?
You can use Aragan Plus regardless of your hair type. It'll help your hair follicles lock in moisture.
Can I use Aragan Plus under eyes?
Yes you can.Aragan Plus can help mask darkness under the eyes.
What does Aragan Plus do to your face?
Aragan Plus helps reduce the visibility of fine lines and wrinkles retaining moisture to the skin.
Can Aragan Plus cause facial hair growth?
Aragan Plus is similar to a fertilizer because it can increase hair growth.
What happen If I missed Aragan Plus?
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.
What happens if I overdose?
Aragan Plus may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing.call a poison control center right away.
