Axatilimab Uses, Dosage, Side Effects and more

Axatilimab is under investigation in clinical trial NCT04301778 (Durvalumab in Combination With a CSF-1R Inhibitor (SNDX-6532) Following Chemo or Radio-embolization for Patients With Intrahepatic Cholangiocarcinoma).

Trade Name Axatilimab
Generic Axatilimab
Axatilimab Other Names anti-Csf1R monoclonal antibody SNDX-6352, Axatilimab
Type
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: January 7, 2025 at 1:49 am

How Axatilimab works

Axatilimab is a high affinity antibody targeting the colony stimulating factor 1 receptors (CSF-1R). Its actions at CSF-1R allows for the regulation of the expansion and infiltration of donor-derived macrophages that mediate chronic graft versus host disease.

Innovators Monograph


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