Azaron

Azaron Uses, Dosage, Side Effects, Food Interaction and all others data.

A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications. Azaron is administered by various routes, including topically.

Used to treat the effects of colds and allergies. Azaron is an antihistamine. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Azaron is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.

Trade Name Azaron
Availability Discontinued
Generic Tripelennamine
Tripelennamine Other Names Tripelennamin, Tripelennamina, Tripélennamine, Tripelennamine, Tripelennaminum
Related Drugs hydroxyzine, loratadine, levocetirizine, Vistaril, Atarax, Xyzal
Type
Formula C16H21N3
Weight Average: 255.358
Monoisotopic: 255.173547687
Groups Approved, Vet approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Azaron
Azaron

Uses

Azaron is a histamine H1 antagonist used to treat hypersensitivity reactions, coughs, and the common cold.

Used for the symptomatic relief of hypersensitivity reactions, coughs, and the common cold.

Azaron is also used to associated treatment for these conditions: Itching caused by Insect Bites, Itching caused by Jellyfish Stings, Itching caused by Nettles

How Azaron works

Azaron binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine.

Toxicity

Symptoms of overdose include clumsiness or unsteadiness, convulsions, drowsiness, dryness of mouth, nose, or throat, feeling faint, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath or troubled breathing, shuffling walk, tic-like movements of head and face, trembling and shaking of hands and trouble in sleeping.

Food Interaction

No interactions found.

[Moderate] GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents.

Use in combination may result in additive central nervous system depression and
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol.

Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

Elimination Route

Well absorbed in the digestive tract.

Innovators Monograph

You find simplified version here Azaron

http://classyfire.wishartlab.com/tax_nodes/C0000000
http://classyfire.wishartlab.com/tax_nodes/C0002448
http://classyfire.wishartlab.com/tax_nodes/C0002279
http://classyfire.wishartlab.com/tax_nodes/C0002673
http://classyfire.wishartlab.com/tax_nodes/C0004802
http://classyfire.wishartlab.com/tax_nodes/C0003901
http://classyfire.wishartlab.com/tax_nodes/C0000283
http://classyfire.wishartlab.com/tax_nodes/C0003886
http://classyfire.wishartlab.com/tax_nodes/C0004144
http://classyfire.wishartlab.com/tax_nodes/C0002239
http://classyfire.wishartlab.com/tax_nodes/C0004139
http://classyfire.wishartlab.com/tax_nodes/C0004557
http://classyfire.wishartlab.com/tax_nodes/C0004150
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:9741
http://www.hmdb.ca/metabolites/HMDB0014930
http://www.genome.jp/dbget-bin/www_bget?cpd:C07180
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5587
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46506125
https://www.chemspider.com/Chemical-Structure.5385.html
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81471
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=10847
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=9741
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL1241
https://zinc.docking.org/substances/ZINC000019117728
http://bidd.nus.edu.sg/group/cjttd/ZFTTDDRUG.asp?ID=DAP000328
http://www.pharmgkb.org/drug/PA164764429
https://www.drugs.com/mtm/tripelennamine.html
https://en.wikipedia.org/wiki/Tripelennamine
*** Taking medicines without doctor's advice can cause long-term problems.
Share