Babimos Bar Uses, Dosage, Side Effects and more
Glycerin is a hyperosmotic laxative, given rectally, which usually produces a bowel movement within 15 minutes to 1 hour. Hyperosmotic laxatives encourage bowel movements by drawing water into the bowel from surrounding tissues. This produces a softer stool mass and increased bowel action. These products are used for fast, predictable relief of occasional constipation.
Glycerin is commonly classified as an osmotic laxative but may act additionally or alternatively through its local irritant effects; it may also have lubricating and fecal softening actions. Glycerin suppositories usually work within 15 to 30 minutes.
Oil extracted from olives . Consists primarily of the glycerides of the fatty acids linoleic, oleic and palmitic. Used as a source of fatty acids in total parenteral nutrition and as an additive in some cosmetic products .
Provides a source of calories and fatty acids .
| Trade Name | Babimos Bar |
| Generic | Olive Oil + Glycerin + Wheat Germ Oil |
| Weight | 2% |
| Type | |
| Therapeutic Class | |
| Manufacturer | Orimax Healthcare |
| Available Country | India |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
For the relief of occasional constipation
For use in adults as a source of calories and fatty acids in total parenteral nutrition . Sometimes used as an additive in cosmetic products.
Babimos Bar is also used to associated treatment for these conditions: Cold Sore, Constipation, Dry Mouth, Dry Skin, Dry throat, Edema of the cerebrum, Hypertension Intracranial, Occasional Constipation, Ocular Discomfort, Ocular Hypertension, Ocular Irritation, Skin Infections, Sore Throat, Mouth soreness, Ocular burning, Bowel preparation therapy, Topical Antisepsis, Skin protectionNutritional supplementation, Total parenteral nutrition therapy
How Babimos Bar works
When administered rectally, glycerin exerts a hygroscopic and/or local irritant action, drawing water from the tissues into the feces and reflexively stimulating evacuation. Glycerin decreases intraocular pressure by creating an osmotic gradient between the blood and intraocular fluid, causing fluid to move out of the aqueous and vitreous humors into the bloodstream.
Fatty acids act as a substrate in energy production through beta-oxidation as well as important components of cell membrane structures and prescursors for bioactive molecules like prostaglandins .
Dosage
Babimos Bar dosage
Children under 2 years: Consult a physician.
Children (2 to 6 years): only 1 Glycerin 1.15 suppository per 24 hours or as directed by a physician.
Adults and Children (From 6 years): only 1 Glycerin 2.30 suppository per 24 hours or as directed by a physician
Insert suppository well up into rectum. Suppository need to melt completely to produce laxative action.
Side Effects
Glycerin when used rectally may cause rectal discomfort or a burning sensation
Toxicity
Glycerol has very low toxicity when ingested ; Rat LD50 (oral)-12600mg/kg Mice LD50 (oral )-4090mg/kg Human TDLo (oral) - 1428mg/kg
Fat overload sydrome is the primary form of toxicity characterized by a sudden deterioration in the patient's condition accompanied by fever, anemia, leukopenia, thrombocytopenia, coagulation disorders, hyperlipidemia, liver fatty infiltration, deteriorating liver function, and central nervous system manifestations such as coma . The precise cause of this is unclear. While it is most likely to occur during overdosage of lipids some occurences have been reported when lipids are administered appropriately. Intraperitoneal LD50 in mice of >50g/kg and intravenous LD50 in rats of 1320mg/kg .
Volume of Distribution
Glycerin is distributed throughout the blood. Although glycerin generally does not appear in ocular fluids, it may enter the orbital sac when the eye is inflamed, with a consequent decrease in osmotic effect.
Elimination Route
Well absorbed orally, poorly absorbed rectally. Studies in humans and animals indicate glycerol is rapidly absorbed in the intestine and the stomach
Half Life
30 - 45 minutes
Elimination Route
Approx 7-14% of dose is excreted unchanged in the urine within 2.5 hr.
Pregnancy & Breastfeeding use
Pregnancy category C. There are no controlled data in human pregnancy
Contraindication
Sensitivity to the ingredients. Do not use unless the patient to be treated is, in fact, constipated.
Storage Condition
Store below 25° C. Protect from moisture.
