Bacampicillin
Bacampicillin Uses, Dosage, Side Effects, Food Interaction and all others data.
Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of cell wall mucopeptides. It is used to cure infection of upper and lower respiratory tract; skin and soft tissue; urinary tract and acute uncomplicated gonococcal urethritis etc.
Bacampicillin is a prodrug of ampicillin and is microbiologically inactive.
Trade Name | Bacampicillin |
Availability | Discontinued |
Generic | Bacampicillin |
Bacampicillin Other Names | Bacampicilina, Bacampicillin, Bacampicilline, Bacampicillinum |
Related Drugs | amoxicillin, doxycycline, ciprofloxacin, cephalexin, metronidazole, azithromycin, clindamycin, ceftriaxone, levofloxacin, Augmentin |
Type | |
Formula | C21H27N3O7S |
Weight | Average: 465.52 Monoisotopic: 465.156970923 |
Groups | Approved, Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Bacampicillin is an ampicillin prodrug used to treat various susceptible bacterial infections in the body, such as respiratory infections and skin and subcutaneous tissue infections.
For infections at the following sites: upper and lower respiratory tract; skin and soft tissue; urinary tract and acute uncomplicated gonococcal urethritis, when due to sensitive strains of the following organisms: Gram-positive: streptococci (including S. faecalis and S. pneumoniae) and nonpenicillinase-producing staphylococci; Gram-negative: H. influenzae, N. gonorrhoeae, E. coli, P. mirabilis, Salmonellae and Shigellae.
Bacampicillin is also used to associated treatment for these conditions: Genital infection, Infections, Intestinal, Lower Respiratory Tract Infection (LRTI), Oral Infection, Pneumonia, Skin and Subcutaneous Tissue Bacterial Infections, Upper Respiratory Tract Infection, Urinary Tract Infection, Susceptible Bacterial Infections
How Bacampicillin works
During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of cell wall mucopeptides.
Food Interaction
- Take separate from antacids. Elevated gastric pH may reduce the bioavailability of bacampicillin.
- Take with or without food. Food may reduce the bioavailability of bacampicillin.
Bacampicillin Drug Interaction
Moderate: quinapril, quinapril, rabeprazole, rabeprazoleUnknown: acetaminophen, acetaminophen, aspirin, aspirin, pioglitazone, pioglitazone, nifedipine, nifedipine, amphetamine / dextroamphetamine, amphetamine / dextroamphetamine, fluorouracil, fluorouracil, amoxicillin / clavulanate, amoxicillin / clavulanate, tiotropium, tiotropium
Bacampicillin Disease Interaction
Major: colitisModerate: mononucleosis, renal dysfunction, hemodialysis
Elimination Route
Absorbed following oral administration.
Innovators Monograph
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