Bardoxolone methyl

Bardoxolone methyl Uses, Dosage, Side Effects, Food Interaction and all others data.

Table Of contents

• Bardoxolone methyl
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Bardoxolone methyl
Generic	Bardoxolone methyl
Bardoxolone methyl Other Names	Bardoxolone methyl
Type
Formula	C32H43NO4
Weight	Average: 505.699 Monoisotopic: 505.319208869
Groups	Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Investigated for use/treatment in lymphoma (unspecified), multiple myeloma, and solid tumors.

How Bardoxolone methyl works

RTA 402 inhibits the activity of nuclear factor kappa-B (NF-kB) activated by tumor necrosis factor (TNF) and other inflammatory agents in a variety of cancer cells. It is a novel targeted cancer therapy with a unique mechanism of action. It exploits fundamental physiological differences between cancerous and noncancerous cells by modulating oxidative stress response pathways. As a result, the drug is toxic to cancer cells but induces protective antioxidant and anti-inflammatory responses in normal cells.

Innovators Monograph

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