Basic FGF
Basic FGF Uses, Dosage, Side Effects, Food Interaction and all others data.
Basic FGF (bFGF) is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of physiologic angiogenesis. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to Fibroblast Growth Factor 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (Fibroblast Growth Factor 1). Although it is not approved for use in Canada or the USA, bFGF is currently undergoing investigation in a number of clinical trials.
| Trade Name | Basic FGF |
| Generic | Basic Fibroblast Growth Factor |
| Basic Fibroblast Growth Factor Other Names | Basic astrolial growth factor, Basic FGF, bFGF, FGF 2, Fibroblast growth factor, basic, Heparin-binding growth factor 2, KCB-1, Recombinant human basic fibroblast growth factor, KCB-1 |
| Type | |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Basic FGF is not currently approved for any FDA or Health Canada approved indications.
Innovators Monograph
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