Bee
Bee Uses, Dosage, Side Effects, Food Interaction and all others data.
Bee is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.
| Trade Name | Bee |
| Generic | Mecobalamin |
| Mecobalamin Other Names | Co-methylcobalamin, MeCbl, Mecobalamin, Mecobalamina, Mecobalaminum, Methyl vitamin B12, Methyl(III)cobalamin, Methylcobalamin |
| Type | Od Tablet |
| Formula | C63H91CoN13O14P |
| Weight | Average: 1344.3823 Monoisotopic: 1343.587806391 |
| Groups | Approved, Investigational |
| Therapeutic Class | Drugs for Megaloblastic Anemia |
| Manufacturer | Kepler Health Care |
| Available Country | India |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Bee is used for-
- Peripheral Neuropathies
- Diabetic Neuropathy
- Verteberal Syndrome
- Nerve Compression Syndrome
- Multiple sclerosis
- Amyotrophic lateral sclerosis
- Parkinson’s disease
- Alzheimer’s disease
- Diabetic retinopathy
- Entrapment neuropathy
- Drug induced neuropathy
- Megaloblastic anemia due to Vitamin B12 deficiency
Bee is also used to associated treatment for these conditions: Vitamin B12 Deficiency, Nutritional supplementation
Dosage
Bee dosage
Tablet: The usual adult dosage is one 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms.
Injection:
- Peripheral neuropathies: The usual adult dosage is one ampoule equivalent to 500 mcg of Bee, administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms.
- Megaloblastic anemia: The usual adult dosage is one ampoule equivalent to 500 mcg of Bee, administered intramuscularly or intravenously three times a week. After about two months of administration, dosage should be changed to one ampoule equivalent to 500 mcg of Bee every one to three months as maintenance therapy
Side Effects
Generally Bee is well tolerated. However, a few side effects like GI discomfort (including anorexia, nausea or diarrhea) & rash may be seen after administration of Bee.
Precaution
The medicine should not be used for months if there is no response at all after its use for a certain period of time.
Interaction
Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives. Reduced effects in anaemia with parenteral chloramphenicol.
Food Interaction
No interactions found.Pregnancy & Breastfeeding use
Not recommended during pregnancy & lactation.
Contraindication
Hypersensitivity to any component of this product.
Special Warning
Use in children: Not recommended.
Storage Condition
Oral: Store at room temperature. Protect from moisture and light.
Parenteral: Store at room temperature. Do not expose to direct light.
Innovators Monograph
You find simplified version here Bee
FAQ
What is Bee used for?
Bee is used to treat vitamin B12 deficiency.
How safe is Bee?
Bee is considered likely safe when used appropriately.
How does Bee work?
Bee works by functioning in the production of a compound called myelin, which covers and protect nerve fibers.
What are the common side effects of Bee?
Common side effects of Bee are include:
- Nausea.
- Vomiting.
- Diarrhea.
- Loss of appetite.
- Headache.
Is Bee safe during pregnancy?
Pregnancy There are no data available for Bee to be used in pregnant women.
Is Bee safe during breastfeeding?
There are no data available for Bee to be used in lactating women.
Can I drink alcohol with Bee?
No interactions were found between Alcohol and Bee. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Can I take Bee daily?
The recommended dose is 500 mcg three times daily or 1500 mcg daily. Most generic vitamins contain cyanocobalamin, which may not be as effective or as beneficial.
How much Bee should I take?
The general recommendation for adults is 2.4 mcg. Older adults, as well as pregnant and breastfeeding women, require higher doses.
Should I take Bee on an empty stomach?
It is a well-known medical fact that water-soluble vitamins are better absorbed on an empty stomach. So, the usual time of taking Bee will be in the morning as the first dose, half an hour before lunch, and 2 hours post a meal.
How long does Bee take to work?
With brisk development of new red blood cells, a response is typically seen within 48 to 72 hours. Bee supplies have reached normal levels,Bee injections will be required every one to three months to avoid the return of symptoms.
How long does Bee supplements stay in my system?
Other studies have shown that Bee has a half-life of around six days in the blood, which means that it would take six days before half of the administered amount is excreted from the body
Can Bee damage my liver?
There is no evidence that the other B vitamins, in physiologic or even super-physiologic high doses cause liver injury or jaundice.
What are the symptoms of high Bee levels?
The study found that high doses of these Bee were actually harmful.
Can Bee cause kidney stones?
Bee have not been shown to be harmful to people with kidney stones.
How long Bee can be taken?
Bee for 2-4 weeks is associated with better outcome in nerve conduction velocity and neuropathic symptoms.
Who should not take Bee?
You should not use Bee if you are allergic to Bee or cobalt. Tell your doctor if you have ever had Leber's disease or other form of optic nerve damage,an iron or folic acid deficiency.
What happens if I miss a dose of Bee?
Use Bee as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.
Can I overdose on Bee?
You cannot overdose on Bee because any excess you simply pee out. If you get Bee shots, you may experience side effects like dizziness, nausea, and fatigue.
