Benzquinamida Uses, Dosage, Side Effects and more

Benzquinamida is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties. The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine H1 receptors.

Benzquinamida is an antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties.

Trade Name Benzquinamida
Generic Benzquinamide
Benzquinamide Other Names benzquinamida, Benzquinamide
Type
Formula C22H32N2O5
Weight Average: 404.4999
Monoisotopic: 404.231122144
Groups Withdrawn
Therapeutic Class
Manufacturer
Available Country
Last Updated: January 7, 2025 at 1:49 am

Uses

Used to prevent and treat nausea and vomiting associated with anesthesia and surgery, administered intramuscularly or intravenously.

How Benzquinamida works

The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine H1 receptors.

Elimination Route

Incomplete, with 33–39% bioavailability via the capsule and suppository routes, relative to the intramuscular route.

Half Life

1-1.6 hours (for all formulations)

Innovators Monograph

*** Taking medicines without doctor's advice can cause long-term problems.
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