Bethene Para Niños
Bethene Para Niños Uses, Dosage, Side Effects, Food Interaction and all others data.
Pantothenic acid is essential to normal epithelial function. The topical use of dexpanthenol, the stable alcoholic analog of pantothenic acid, is based on good skin penetration and high local concentrations of dexpanthenol when administered in an adequate vehicle, such as water-in-oil emulsions. Topical dexpanthenol acts like a moisturizer, improving stratum corneum hydration, reducing trans-epidermal water loss and maintaining skin softness and elasticity.Bethene Para Niños is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Bethene Para Niños is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the epithelium.Dermatological effects of the topical use of dexpanthenol include increased fibroblast proliferation and accelerated re-epithelialization in wound healing. Furthermore, it acts as a topical protectant, moisturizer, and has demonstrated anti-inflammatory properties
Pantothenic acid is a precursor of coenzyme A, which serves as a cofactor for a variety of enzyme-catalyzed reactions involving transfer of acetyl groups. The final step in the synthesis of acetylcholine consists of the choline acetylase transfer of acetyl group from acetylcoenzyme A to choline. Acetylcholine is the neurohumoral transmitter in the parasympathetic system and as such maintains the normal functions of the intestine. Decrease in acetylcholine content would result in decreased peristalsis and in extreme cases adynamic ileus.
Trade Name | Bethene Para Niños |
Availability | Discontinued |
Generic | Dexpanthenol |
Dexpanthenol Other Names | Bepanthen, Bepanthene, Bepantol, D-panthenol, D-panthenol 50, D-Pantothenol, D-Pantothenyl alcohol, Dexpantenol, Dexpanthenol, Dexpanthenolum, Pantol, Pantothenyl alcohol, Provitamin B |
Type | |
Formula | C9H19NO4 |
Weight | Average: 205.2515 Monoisotopic: 205.131408101 |
Protein binding | Plasma protein binding have not been reported. |
Groups | Approved |
Therapeutic Class | Miscellaneous topical agents |
Manufacturer | |
Available Country | Colombia |
Last Updated: | September 19, 2023 at 7:00 am |
![Bethene Para Niños Bethene Para Niños](https://www.medicinesfaq.com/media/png/bethene-para-ni-os.png)
Uses
Bethene Para Niños is used for-
- For prevention and treatment of diaper rash in infants.
- For prevention and treatment of cracked or sore nipples in nursing women.
- For prevention and treatment of chafed, cracked or split skin.
- For treatment of light skin wounds and dry skin
Bethene Para Niños is also used to associated treatment for these conditions: Allergic Rhinitis (AR), Bursitis, Canker Sore, Contusions, Dermabrasion, Diaper Rash, Dry Skin, Edema, Hoarseness, Inflammation, Inflammation of Mouth, Insect Bites, Lateral Epicondylitis, Lesions of the Mucous Membranes, Nasal Congestion, Pharyngeal inflammation, Pruritus, Respiratory Tract Infections (RTI), Seasonal Allergic Rhinitis, Sinusitis, Skin Roughness, Sore Throat, Sunburn, Tendinitis, Tooth Extraction Site Healing, Traumatic Injuries caused by Dental Prosthesis, Urticaria, Vitamin Deficiency, Wounds caused by Surgery, Oral of the Tonsils, Dry, cracked skin, Dryness of the nose, Superficial Conjunctival injuries, Superficial Corneal injuries, Superficial Traumatic Injuries of the Nasal Mucosa, Superficial Wounds, Irrigation therapy, Nutritional supplementation, Oropharyngeal antisepsis, Vitamin supplementation
How Bethene Para Niños works
Bethene Para Niños is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Bethene Para Niños is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the epithelium.
Dermatological effects of the topical use of dexpanthenol include increased fibroblast proliferation and accelerated re-epithelialization in wound healing. Furthermore, it acts as a topical protectant, moisturizer, and has demonstrated anti-inflammatory properties .
Dosage
Bethene Para Niños dosage
Check with the doctor or pharmacist if you are unsure how to use Bethene Para Niños.
The usual dosage is generally:
- Diaper rash: Apply a thin layer on the baby’s bottom at every diaper change.
- Nipples: Apply a thin layer on the nipples after each nursing session. Wash the nipples thoroughly before the next nursing session.
- Dry/cracked skin or light wounds and chafed skin: Apply to the dry areas and/or to the wound up to 3 times a day.
Side Effects
As with any medicine, use of Bethene Para Niños may cause side effects in some users. Do not be alarmed by the list of side effects. You may not suffer from any of them. Discontinue use and refer to a doctor immediately in the event of: Allergic reaction and/or allergic skin reaction such as: atopic dermatitis, allergic dermatitis, pruritus, redness, rash, eczema, urticaria, local irritation or blistering. If a side effect occurs, worsens, or if you suffer from a side effect not mentioned in this leaflet, consult with the doctor.
Toxicity
Mouse LD50 : 9gm/kg (Intraperitoneal) Mouse: LD50 7gm/kg (Intravenous) Mouse: LD50 15gm/kg (Oral) Rabbit LD50 4gm/kg (Oral)
Food Interaction
No interactions found.Volume of Distribution
Bethene Para Niños is readily converted to pantothenic acid which is widely distributed into body tissues, mainly as coenzyme A. Highest concentrations are found in the liver, adrenal glands, heart, and kidneys.
Elimination Route
Bethene Para Niños is soluble in water and alcohol, although insoluble in fats and oil based substances. With the appropriate vehicle, Bethene Para Niños is easily penetrated into the skin. Rate of penetration and absorption is reduced when Bethene Para Niños is administered as an oil/water formula.
Half Life
Half life have not been reported
Elimination Route
Milk of nursing mothers receiving a normal diet contains about 2 ug of pantothenic acid per mL. About 70% of an oral dose of pantothenic acid is excreted unchanged in urine and about 30% in feces.
Storage Condition
Do not store above 30 degree Celsius. Keep away from light and out of the reach of children.
Innovators Monograph
You find simplified version here Bethene Para Niños