Bicarbonate Component (HCO3 Hemodialysis Solution)

Bicarbonate Component (HCO3 Hemodialysis Solution) Uses, Dosage, Side Effects, Food Interaction and all others data.

Sodium Chloride 6.6 %

Sodium Hydrogen Carbonate 3.1%

Highly purified water

Sodium chloride is the major extracellular cation. It is important in electrolyte and fluid balance, osmotic pressure control and water distribution as it restores sodium ions. It is used as a source of electrolytes and water for hydration, treatment of metabolic acidosis, priming solution in haemodialysis and treatment of hyperosmolar diabetes. It is also used as diluents for infusion of compatible drug additives.

Sodium bicarbonate raises blood and urinary pH by dissociation to provide bicarbonate ions, which neutralises the hydrogen ion concentration. It also neutralises gastric acid via production of carbon dioxide.

Table Of contents

• Bicarbonate Component (HCO3 Hemodialysis Solution)
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Bicarbonate Component (HCO3 Hemodialysis Solution)
Generic	Bicarbonate Component (HCO3 Hemodialysis Solution)
Type
Therapeutic Class	Haemodialysis solutions
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Acute renal failure, Chronic renal failure, Dialysis, Haemodialysis

Dosage

Bicarbonate Component (HCO3 Hemodialysis Solution) dosage

5 liter Concentrate per dialysis or as required.

Precaution

Do not use sol A or sol B alone. It must be diluted immediately before use with water of suitable quality. Discard container in case of visible solid particles inside. It’s not for IV injection or infusion.

Interaction

Sodium bicarbonate: Increases toxicity of amphetamines, ephedrine, pseudoephedrine, flecainide, quinidine and quinine. Decreases effects of lithium, chlorpropamide and salicylates due to increased clearance. May affect the absorption of certain drugs due to raised intra-gastric pH.

Sodium chloride: May affect serum concentrations of lithium.

Pregnancy & Breastfeeding use

Pregnancy Category- X. Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Contraindication

Known hypersensitivity to any of the ingredients of Bicarbonate Component (HCO3 Hemodialysis Solution).

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