Bigvin Md
Bigvin Md Uses, Dosage, Side Effects, Food Interaction and all others data.
Bigvin Md is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.
| Trade Name | Bigvin Md |
| Generic | Mecobalamin |
| Mecobalamin Other Names | Co-methylcobalamin, MeCbl, Mecobalamin, Mecobalamina, Mecobalaminum, Methyl vitamin B12, Methyl(III)cobalamin, Methylcobalamin |
| Type | Tablet |
| Formula | C63H91CoN13O14P |
| Weight | Average: 1344.3823 Monoisotopic: 1343.587806391 |
| Groups | Approved, Investigational |
| Therapeutic Class | Drugs for Megaloblastic Anemia |
| Manufacturer | Bestochem Formulations India Ltd |
| Available Country | India |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Bigvin Md is used for-
- Peripheral Neuropathies
- Diabetic Neuropathy
- Verteberal Syndrome
- Nerve Compression Syndrome
- Multiple sclerosis
- Amyotrophic lateral sclerosis
- Parkinson’s disease
- Alzheimer’s disease
- Diabetic retinopathy
- Entrapment neuropathy
- Drug induced neuropathy
- Megaloblastic anemia due to Vitamin B12 deficiency
Bigvin Md is also used to associated treatment for these conditions: Vitamin B12 Deficiency, Nutritional supplementation
Dosage
Bigvin Md dosage
Tablet: The usual adult dosage is one 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms.
Injection:
- Peripheral neuropathies: The usual adult dosage is one ampoule equivalent to 500 mcg of Bigvin Md, administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms.
- Megaloblastic anemia: The usual adult dosage is one ampoule equivalent to 500 mcg of Bigvin Md, administered intramuscularly or intravenously three times a week. After about two months of administration, dosage should be changed to one ampoule equivalent to 500 mcg of Bigvin Md every one to three months as maintenance therapy
Side Effects
Generally Bigvin Md is well tolerated. However, a few side effects like GI discomfort (including anorexia, nausea or diarrhea) & rash may be seen after administration of Bigvin Md.
Precaution
The medicine should not be used for months if there is no response at all after its use for a certain period of time.
Interaction
Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives. Reduced effects in anaemia with parenteral chloramphenicol.
Food Interaction
No interactions found.Pregnancy & Breastfeeding use
Not recommended during pregnancy & lactation.
Contraindication
Hypersensitivity to any component of this product.
Special Warning
Use in children: Not recommended.
Storage Condition
Oral: Store at room temperature. Protect from moisture and light.
Parenteral: Store at room temperature. Do not expose to direct light.
Innovators Monograph
You find simplified version here Bigvin Md
FAQ
What is Bigvin Md used for?
Bigvin Md is used to treat vitamin B12 deficiency.
How safe is Bigvin Md?
Bigvin Md is considered likely safe when used appropriately.
How does Bigvin Md work?
Bigvin Md works by functioning in the production of a compound called myelin, which covers and protect nerve fibers.
What are the common side effects of Bigvin Md?
Common side effects of Bigvin Md are include:
- Nausea.
- Vomiting.
- Diarrhea.
- Loss of appetite.
- Headache.
Is Bigvin Md safe during pregnancy?
Pregnancy There are no data available for Bigvin Md to be used in pregnant women.
Is Bigvin Md safe during breastfeeding?
There are no data available for Bigvin Md to be used in lactating women.
Can I drink alcohol with Bigvin Md?
No interactions were found between Alcohol and Bigvin Md. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Can I take Bigvin Md daily?
The recommended dose is 500 mcg three times daily or 1500 mcg daily. Most generic vitamins contain cyanocobalamin, which may not be as effective or as beneficial.
How much Bigvin Md should I take?
The general recommendation for adults is 2.4 mcg. Older adults, as well as pregnant and breastfeeding women, require higher doses.
Should I take Bigvin Md on an empty stomach?
It is a well-known medical fact that water-soluble vitamins are better absorbed on an empty stomach. So, the usual time of taking Bigvin Md will be in the morning as the first dose, half an hour before lunch, and 2 hours post a meal.
How long does Bigvin Md take to work?
With brisk development of new red blood cells, a response is typically seen within 48 to 72 hours. Bigvin Md supplies have reached normal levels,Bigvin Md injections will be required every one to three months to avoid the return of symptoms.
How long does Bigvin Md supplements stay in my system?
Other studies have shown that Bigvin Md has a half-life of around six days in the blood, which means that it would take six days before half of the administered amount is excreted from the body
Can Bigvin Md damage my liver?
There is no evidence that the other B vitamins, in physiologic or even super-physiologic high doses cause liver injury or jaundice.
What are the symptoms of high Bigvin Md levels?
The study found that high doses of these Bigvin Md were actually harmful.
Can Bigvin Md cause kidney stones?
Bigvin Md have not been shown to be harmful to people with kidney stones.
How long Bigvin Md can be taken?
Bigvin Md for 2-4 weeks is associated with better outcome in nerve conduction velocity and neuropathic symptoms.
Who should not take Bigvin Md?
You should not use Bigvin Md if you are allergic to Bigvin Md or cobalt. Tell your doctor if you have ever had Leber's disease or other form of optic nerve damage,an iron or folic acid deficiency.
What happens if I miss a dose of Bigvin Md?
Use Bigvin Md as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.
Can I overdose on Bigvin Md?
You cannot overdose on Bigvin Md because any excess you simply pee out. If you get Bigvin Md shots, you may experience side effects like dizziness, nausea, and fatigue.
