Bimoclomol
Bimoclomol Uses, Dosage, Side Effects, Food Interaction and all others data.
Bimoclomol is an investigational drug that induces stress proteins and has cytoprotective effects.
Trade Name | Bimoclomol |
Generic | Bimoclomol |
Bimoclomol Other Names | Bimoclomol |
Type | |
Formula | C14H20ClN3O2 |
Weight | Average: 297.781 Monoisotopic: 297.124404606 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in neuropathy (diabetic) and wounds.
How Bimoclomol works
Bimoclomol binds to HSF-1 and induces a prolonged binding of HSF-1 to the respective DNA elements. Since HSF-1 does not bind to DNA in the absence of stress, the bimoclomol-induced extension of HSF-1/DNA interaction may contribute to the chaperone co-induction of bimoclomol observed previously. These findings indicate that bimoclomol may be of value in targeting HSF-1 so as to induce up-regulation of protective Hsp-s in a non-stressful manner and for therapeutic benefit.
Innovators Monograph
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