Bimoclomol Uses, Dosage, Side Effects and more
Bimoclomol is an investigational drug that induces stress proteins and has cytoprotective effects.
| Trade Name | Bimoclomol |
| Generic | Bimoclomol |
| Bimoclomol Other Names | Bimoclomol |
| Type | |
| Formula | C14H20ClN3O2 |
| Weight | Average: 297.781 Monoisotopic: 297.124404606 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in neuropathy (diabetic) and wounds.
How Bimoclomol works
Bimoclomol binds to HSF-1 and induces a prolonged binding of HSF-1 to the respective DNA elements. Since HSF-1 does not bind to DNA in the absence of stress, the bimoclomol-induced extension of HSF-1/DNA interaction may contribute to the chaperone co-induction of bimoclomol observed previously. These findings indicate that bimoclomol may be of value in targeting HSF-1 so as to induce up-regulation of protective Hsp-s in a non-stressful manner and for therapeutic benefit.
