Boots Derma Care Eczema & Dermatitis Flare-Up 0.05%
Boots Derma Care Eczema & Dermatitis Flare-Up 0.05% Uses, Dosage, Side Effects, Food Interaction and all others data.
Boots Derma Care Eczema & Dermatitis Flare-Up 0.05% is synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.
Boots Derma Care Eczema & Dermatitis Flare-Up 0.05% is a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents. Boots Derma Care Eczema & Dermatitis Flare-Up 0.05% is a selective glucocorticoid receptor agonist.
| Trade Name | Boots Derma Care Eczema & Dermatitis Flare-Up 0.05% |
| Availability | Prescription only |
| Generic | Alclometasone |
| Alclometasone Other Names | Alclometasone |
| Related Drugs | Humira, Cosentyx, Dupixent, prednisone, methotrexate, Remicade, Stelara, cyclosporine, infliximab, Temovate |
| Type | |
| Formula | C22H29ClO5 |
| Weight | Average: 408.916 Monoisotopic: 408.170351745 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | United Kingdom |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Boots Derma Care Eczema & Dermatitis Flare-Up 0.05% is a topical corticosteroid used to relieve the symptoms of corticosteroid-responsive dermatoses.
For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Boots Derma Care Eczema & Dermatitis Flare-Up 0.05% is also used to associated treatment for these conditions: Dermatosis
How Boots Derma Care Eczema & Dermatitis Flare-Up 0.05% works
The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. Boots Derma Care Eczema & Dermatitis Flare-Up 0.05% initially binds the corticosteroid receptor. This complex migrates to the nucleus where it binds to different glucocorticoid response elements on the DNA. This in turn enhances and represses various genes, especially those involved in inflammatory pathways.
Toxicity
Symptoms of overdose include suppression of adrenal glands, temporary decrease in white blood cell counts, symptoms of hypersensitivity (such as skin rash, hives, itching, and difficulty breathing), and increased susceptibility to infection.
Food Interaction
No interactions found.Boots Derma Care Eczema & Dermatitis Flare-Up 0.05% Disease Interaction
Moderate: diabetes, diaper rash, hyperadrenocorticism, infections, ocular toxicities
Elimination Route
Topical corticosteroids can be absorbed from normal intact skin. Studies have shown that approximately 3% of steroid is absorbed during 8 hours of contact with intact skin of normal volunteers.
Innovators Monograph
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