Boots Once Weekly Fungal Nail Treatment 5%
Boots Once Weekly Fungal Nail Treatment 5% Uses, Dosage, Side Effects, Food Interaction and all others data.
Boots Once Weekly Fungal Nail Treatment 5% is a topical antimycotic. Boots Once Weekly Fungal Nail Treatment 5% belongs to a new chemical class, and its fungicidal action is based on an alteration of the fungal cell membrane targeted primarily on sterol biosynthesis. The ergosterol content is reduced, and at the same time unusual sterically nonplanar sterols accumulate.
Trade Name | Boots Once Weekly Fungal Nail Treatment 5% |
Generic | Amorolfine |
Amorolfine Other Names | Amorolfin, Amorolfina, Amorolfine |
Type | |
Formula | C21H35NO |
Weight | Average: 317.517 Monoisotopic: 317.271864751 |
Groups | Approved, Investigational |
Therapeutic Class | Topical Antifungal preparations |
Manufacturer | |
Available Country | United Kingdom |
Last Updated: | September 19, 2023 at 7:00 am |
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Uses
Boots Once Weekly Fungal Nail Treatment 5% Hydrochloride is used for Dermatomycoses caused by dermatophytes: tinea pedis (athlete's foot), tinea cruris, tinea inguinalis, tinea corporis, tinea manuum. Pityriasis versicolor.
Boots Once Weekly Fungal Nail Treatment 5% is also used to associated treatment for these conditions: Dermatomycoses, Fungus, Nail, Pityriasis versicolor, Tinea Corporis, Tinea Cruris, Tinea Pedis, Tinea inguinalis, Tinea manuum, Cutaneous candidiasis
Dosage
Boots Once Weekly Fungal Nail Treatment 5% dosage
Adult: To be applied to affected skin areas once daily following cleansing (in the evening). The treatment should be continued without interruption until clinical cure, and for 3-5 days thereafter. The required duration of treatment depends on the species of fungi and on the localisation of the infection. In general, treatment should be continued for at least two to three weeks. With foot mycoses, up to six weeks of therapy may be necessary.
Elderly: There are no specific dosage recommendations for use in elderly patients.
Children: There are no specific dosage recommendations for children owing to the lack of clinical experience available to date.
Side Effects
Side effects are Skin Irritation, erythema, pruritus, skin burning sensation, Hypersensitivity (systemic allergic reaction).
Precaution
Avoid contact of Boots Once Weekly Fungal Nail Treatment 5% cream with eyes, ears and mucous membranes. This medicinal product contains stearyl alcohol which may cause local skin reaction (e.g. contact dermatitis) Owing to the lack of clinical experience available to date, the use of Boots Once Weekly Fungal Nail Treatment 5% 0.25% cream in children is not recommended. A systemic or local allergic reaction could possibly occur after use of this product. If this happens, the product should be stopped immediately and medical advice should be sought. Remove the product carefully by cleaning the skin. The product should not be reapplied.
Interaction
There are no specific studies involving concomitant treatment with other topical medicines. Use of nail varnish or artificial nails should be avoided during treatment.
Pregnancy & Breastfeeding use
No experience exists of use during pregnancy and nursing, therefore, the use of Boots Once Weekly Fungal Nail Treatment 5% should be avoided during pregnancy and lactation. Reproductive toxicology studies showed no evidence of teratogenicity in laboratory animals but embryotoxicity was observed at high oral doses. The systemic absorption of amorolfine during and after topical administration is very low and therefore the risk to the human foetus appears to be negligible. Boots Once Weekly Fungal Nail Treatment 5% Cream should not be used during pregnancy and/or lactation unless clearly necessary. Breast-feeding women must not use the cream in the breast area.
Contraindication
Boots Once Weekly Fungal Nail Treatment 5% cream must not be reused by patients who have shown hypersensitivity to the active substance or to any of the excipients.
Acute Overdose
Boots Once Weekly Fungal Nail Treatment 5% is for topical use. In the event of accidental oral ingestion, an appropriate method of gastric emptying may be used.
Storage Condition
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Innovators Monograph
You find simplified version here Boots Once Weekly Fungal Nail Treatment 5%
Boots Once Weekly Fungal Nail Treatment 5% contains Amorolfine see full prescribing information from innovator Boots Once Weekly Fungal Nail Treatment 5% Monograph, Boots Once Weekly Fungal Nail Treatment 5% MSDS, Boots Once Weekly Fungal Nail Treatment 5% FDA label