Bovine Fibrinolysin
Bovine Fibrinolysin Uses, Dosage, Side Effects, Food Interaction and all others data.
Bovine Fibrinolysin consists of two polypeptide chains, one light and one heavy, linked by a disulfide bond. The light chain has a molecular weight of approximately 27,000 Da and contains the active center of Bovine Fibrinolysin; the heavy chain has a molecular weight of approximately 57,000 Da. Bovine Fibrinolysin is used as a local healing ointment when combined together with the enzyme deoxyribonuclease I (extracted from bovine pancreas). Bovine Fibrinolysin and deoxyribonuclease both act as lytic enzymes. The combination is available as ointment containing 1 BU (Biological Unit) Bovine Fibrinolysin and 666 BUs desoxyribonuclease per gram. The ointment is marketed by Pfizer under the brand name Fibrolan in a variety of countries (e.g. Switzerland). It is currently not approved in the USA.
| Trade Name | Bovine Fibrinolysin |
| Generic | Fibrinolysin |
| Fibrinolysin Other Names | Bovine Fibrinolysin, Bovine Plasmin, Fibrinolysin (human), Fibrinolysin, human, Plasmin (bos taurus), Plasmin (bovine), Plasmin bovine |
| Type | |
| Formula | C3848H5912N1096O1185S60 |
| Weight | 88411.4 Da |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Bovine Fibrinolysin assists with the healing of minor burns, superficial wounds, ulcers, surgical wounds, and superficial hematomas.
How Bovine Fibrinolysin works
Bovine Fibrinolysin attacks and inactivates fibrin molecules occurring in undesirable exudates on the surface of the human body and on human mucosa, e.g., in superficial wounds and burns, while desoxyribonuclease targets and destroys (human) DNA. The combination of the two enzymes has a synergistic effect on necrotic but not on living tissue.
Food Interaction
No interactions found.Half Life
Almost completely inactivated after 24 hours.
Innovators Monograph
You find simplified version here Bovine Fibrinolysin
