Bumirate
Bumirate Uses, Dosage, Side Effects, Food Interaction and all others data.
Bumirate Citrate belongs to the anti-cough medicines of central action. It exerts expectorant, moderate bronchodilating and anti-inflammatory action. Bumirate Citrate also increases the spirometery indexes and blood oxygenation. It is safe and non-sedating which is neither chemically nor pharmacologically related to opium alkaloids. The active metabolites of Bumirate Citrate have also antitussive action.
| Trade Name | Bumirate |
| Generic | Butamirate |
| Butamirate Other Names | Butamirate |
| Weight | 7.5mg/5ml |
| Type | Syrup |
| Formula | C18H29NO3 |
| Weight | Average: 307.434 Monoisotopic: 307.214743798 |
| Groups | Experimental |
| Therapeutic Class | Cough suppressant |
| Manufacturer | Hudson Pharmaceuticals Ltd |
| Available Country | Bangladesh |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Bumirate Citrate is used for acute cough of any etiology, suppression of pre-& post-operative cough in surgery & bronchoscopy and suppression of whooping cough.
Bumirate is also used to associated treatment for these conditions: Cough
Dosage
Bumirate dosage
Tablet:
- Adult: 2-3 tablets daily at 8 to 12 hours intervals,
- Adolescents over 12 years old: 1-2 tablets daily.
Syrup:
- Children (3-6 years): 5 ml 3 times daily,
- Children (6-12 years): 10 ml 3 times daily,
- Adolescent: 15 ml 3 times daily,
- Adult: 15 ml 4 times daily.
PediatricDrops:
- Children (1-3 years): 0.75 ml 4 times daily,
- Children (2 months-1 year): 0.50 ml 4 times daily.
Side Effects
Tolerance of Bumirate Citrate is good. Adverse reactions such as rash, nausea, diarrhea and vertigo have been observed in a few rare cases, resolving after dose reduction or treatment withdrawal.
Precaution
Avoid simultanous administration of expectorants. Minor influence on the ability to drive & use machines. Avoid during pregnancy (1st 3 months) & lactation.
Tablet: Rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption.
Syrup: Sorbitol: Rare hereditary problems of fructose intolerance. Contains ethanol.
Interaction
Avoid use with expectorants.
Pregnancy & Breastfeeding use
Bumirate Citrate should not be used during the first trimester of pregnancy. During the remainder of pregnancy, it can be used if indicated by a physician but with caution. As a general rule, for safety reasons, in the absence of data on elimination of the active substance in breast milk, the benefits of Bumirate Citrate administration during breast feeding should be carefully weighed against the risks.
Contraindication
Bumirate Citrate is contraindicated in patients with known hypersensitivity to any component of the formulation.
Acute Overdose
Accidental overdose with Bumirate Citrate can cause the following symptoms: drowsiness, nausea, vomiting, diarrhea, loss of balance and hypotension. Standard emergency procedures should be followed: activated charcoal, saline laxatives and standard cardio-respiratory resuscitation.
Storage Condition
Do not store above 30 0 C. Keep away from light and out of the reach of children.
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