Cacao Seed Oil

Cacao Seed Oil Uses, Dosage, Side Effects, Food Interaction and all others data.

Cacao Seed Oil is an edible natural fat obtained from the Theobroma cocoa seeds that is predominantly found in dark chocolate . It is a rich source of monounsaturated and saturated fatty acids [A33040] that mainly contains approximately 33% Oleic Acid, 25% Palmitic Acid, and 33% Stearic acid but does not contain caffeine or theobromine. Fat cocoa solids, including cocoa butter, have lower phenolic content than non-fat cocoa solids but may contain some polyphenols of different structures of flavonoids with antioxidant properties .

Cacao Seed Oil is included in chocolate and other food products, and can also be found in over-the-counter skin products such as lotions, creams, and bars intended to maintain skin softness. While cocoa butter has skin moisturizing properties, it was not shown to reduce the likelihood of developing of striae gravidarum, or stretch marks, in a double-blind, randomized clinical trial of women in the first trimester . Still, it is a common active ingredient for prevention of skin dryness in cosmetic and skincare products. Oftentimes cocoa butter is used in over-the-counter pharmaceutical products and suppositories. The lipid-lowering effects of cocoa butter have been studied and investigated, as fatty acid constituents of cocoa butter are known to exhibit lipid-lowering properties. Dyslipidemia is characterized by elevated levels of plasma triglyceride and very-low-density lipoprotein (VLDL) cholesterol due to overproduction of large triglyceride-enriched VLDL cholesterol particles . Cacao Seed Oil has shown to reduce VLDL cholesterol levels in animal studies, suggesting its potential use in lipid disorders.

In a rat study, treatment with 10% cocoa butter has been shown to lower liver cholesterol and triglyceride levels without affecting the serum cholesterol levels . Supplementation of cocoa butter reduced the level of creatinine in vitro, suggesting that cocoa butter may also beneficial to renal function via antioxidant effects .

Cacao Seed Oil
Uses
Dosage
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Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
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Trade Name	Cacao Seed Oil
Generic	Cocoa butter
Cocoa butter Other Names	Cacao butter, Cacao seed oil, fermented, Oil, cocoa butter, Oil,cocoa butter, Theobroma cacao (cocoa) seed butter, Theobroma cacao oil, Theobroma oil
Type
Protein binding	No pharmacokinetic data available.
Groups	Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Indicated for topical use in over-the-counter skin products for the treatment of skin dryness and reduction of striae gravidarum (stretch marks).

How Cacao Seed Oil works

Cacao Seed Oil is comprised of saturated fatty acids that exert a neutral cholesterolemic response in humans . Stearic acid is one of the major constituent in cocoa butter that is a non-atherogenic type of dietary saturated fat . Although it is a saturated fatty acid known to elevate plasma lipids and lipoproteins, stearic acid from plant sources differs from animal-derived sources of stearic acid . Possible explanations for this unique property may include chain length, inefficient absorption, metabolism kinetics, and hepatic desaturation of stearic into oleic acid . Apart from its lipid-lowering actions, stearic acid may also mediate actions on hemostasis and thrombosis which still remain inconclusive . In vitro, stearic acid was demonstrated to promote platelet aggregation and factor VII coagulant activity; however in vivo preliminary studies mixed results .

Cacao Seed Oil may contain flavonoids that elicit antioxidant, anti-platelet, anti-inflammatory effects, as well as possibly increasing HDL, lowering blood pressure, and improving endothelial function . They inhibit lipid peroxidation, scavenge reactive oxygen species, and attenuate photochemical overproduction of ROS thus minimize UV-induced photodamage and signs of aging on the skin .