Camviz
Camviz Uses, Dosage, Side Effects, Food Interaction and all others data.
Camviz is an NSAID, belonging to the oxicam group. It reversibly inhibits cyclooxygenase-1 and -2 (COX-1 and -2) enzymes, which results in decreased formation of prostaglandin precursors.
Camviz is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Camviz works by reducing hormones that cause inflammation and pain in the body. Camviz is used to reduce the pain, inflammation, and stiffness caused by rheumatoid arthritis and osteoarthritis.
Trade Name | Camviz |
Availability | Prescription only |
Generic | Piroxicam |
Piroxicam Other Names | Piroxicam, Piroxicam betadex, Piroxicamum, Pyroxycam |
Related Drugs | Humira, Buprenex, aspirin, prednisone, ibuprofen, acetaminophen, tramadol, meloxicam, naproxen, diclofenac |
Type | Injection |
Formula | C15H13N3O4S |
Weight | Average: 331.346 Monoisotopic: 331.062676609 |
Groups | Approved, Investigational |
Therapeutic Class | Drugs for Osteoarthritis, Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs) |
Manufacturer | Agron Remedies |
Available Country | India |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Carefully consider the potential benefits and risks of Camviz and other treatment options before deciding to use Camviz. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals. Camviz is used for relief of the signs and symptoms of osteoarthritis, for relief of the signs and symptoms of rheumatoid arthritis.
Camviz is also used to associated treatment for these conditions: Ankylosing Spondylitis (AS), Osteoarthritis (OA), Rheumatoid Arthritis
How Camviz works
The antiinflammatory effect of Camviz may result from the reversible inhibition of cyclooxygenase, causing the peripheral inhibition of prostaglandin synthesis. The prostaglandins are produced by an enzyme called Cox-1. Camviz blocks the Cox-1 enzyme, resulting into the disruption of production of prostaglandins. Camviz also inhibits the migration of leukocytes into sites of inflammation and prevents the formation of thromboxane A2, an aggregating agent, by the platelets.
Dosage
Camviz dosage
Oral-
Ankylosing spondylitis, Osteoarthritis, Rheumatoid arthritis:
- Adult: 20 mg daily as a single dose, divided doses may be used if necessary. Treatment should be reviewed w/in 14 days of starting.
- Elderly: Use the lowest effective dose for the shortest duration.
Should be taken with food.
Side Effects
Oedema, CHF, HTN, syncope, tachycardia; anorexia, abdominal pain, constipation, diarrhoea, dyspepsia, flatulence, heartburn, nausea, vomiting, dry mouth, esophagitis, gastritis, glossitis, haematemesis, melaena, stomatitis; anaemia, increased bleeding time, ecchymosis, eosinophilia, epistaxis, leucopenia, thrombocytopenia; cystitis, dysuria, haematuria, hyperkalaemia, interstitial nephritis, nephritic syndrome, oliguria/polyuria, proteinuria, renal failure; dizziness, headache, anxiety, asthenia, confusion, depression, dream abnormalities, drowsiness, insomnia, malaise, nervousness, paraesthesia, somnolence, tremors, vertigo; tinnitus, blurred vision; elevated LFT results; pruritus, rash, alopecia, bruising, desquamation, erythema, petechial rash, photosensitivity, purpura, sweating, serum sickness-like reactions; fever, infection, sepsis, wt changes, asthma, dyspnoea.
Toxicity
Symptoms of overdose include drowsiness, nausea, stomach pain, and/or vomiting.
Precaution
Patient with known CV disease or risk factors for CV disease, fluid retention or heart failure, cerebrovascular disease, uncontrolled HTN, asthma. Elderly. Renal and hepatic impairment. Pregnancy and lactation.
Interaction
Increased risk of GI bleeding with anti-platelets and SSRIs. May exacerbate cardiac failure, reduce GFR and increase plasma glycoside levels. Increased risk of nephrotoxicity with ciclosporin and tacrolimus. Increased absorption with cimetidine. Increased risk of GI ulceration with corticosteroids. May interfere with the natriuretic action of diuretics. May displace other highly protein-bound drugs. May increase steady state plasma lithium levels. May antagonise the effect of antihypertensives. May reduce the excretion of methotrexate, leading to acute toxicity. Increased risk of convulsions with quinolones. May interfere with mifepristone-mediated termination of pregnancy.
Food Interaction
- Avoid alcohol.
- Take with food.
Camviz Alcohol interaction
[Moderate] GENERALLY AVOID:
The concurrent use of aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) and ethanol may lead to gastrointestinal (GI) blood loss.
The mechanism may be due to a combined local effect as well as inhibition of prostaglandins leading to decreased integrity of the GI lining.
Patients should be counseled on this potential interaction and advised to refrain from alcohol consumption while taking aspirin or NSAIDs.
Camviz Hypertension interaction
[Major] Fluid retention and edema have been reported in association with the use of nonsteroidal anti-inflammatory drugs (NSAIDs).
Therapy with NSAIDs should be administered cautiously in patients with preexisting fluid retention, hypertension, or a history of heart failure.
Blood pressure and cardiovascular status should be monitored closely during the initiation of NSAID treatment and throughout the course of therapy.
Hypertension interaction[Moderate] Nonsteroidal anti-inflammatory drugs (NSAIDs), including topicals, can lead to new onset of hypertension or worsening of preexisting hypertension, either of which can contribute to the increased incidence of cardiovascular events.
NSAIDs should be used with caution in patients with hypertension.
Blood pressure should be monitored closely during the initiation of NSAID therapy and throughout the course of therapy.
Camviz Drug Interaction
Major: celecoxibModerate: duloxetine, omega-3 polyunsaturated fatty acids, metoprolol, sertralineUnknown: amphetamine / dextroamphetamine, zolpidem, diphenhydramine, calcium / vitamin d, atorvastatin, pregabalin, esomeprazole, acetaminophen, montelukast, levothyroxine, cyanocobalamin, ascorbic acid, cholecalciferol, alprazolam, cetirizine
Camviz Disease Interaction
Major: asthma, fluid retention, GI toxicity, rash, renal toxicities, thrombosisModerate: anemia, heart failure, hepatotoxicity, hyperkalemia, hypertension, platelet aggregation inhibition
Volume of Distribution
- 0.14 L/kg
Elimination Route
Well absorbed following oral administration.
Half Life
30 to 86 hours
Elimination Route
Camviz and its biotransformation products are excreted in urine and feces, with about twice as much appearing in the urine as in the feces. Approximately 5% of a piroxicam dose is excreted unchanged. However, a substantial portion of piroxicam elimination occurs by hepatic metabolism. Camviz is excreted into human milk.
Pregnancy & Breastfeeding use
Pregnancy catagort C (in 1st & 2nd trimester), D (in 3rd trimester)
Contraindication
Hypersensitivity or asthma-type reactions to piroxicam, aspirin or other NSAIDs. History or active GI ulceration, bleeding and perforation; history of GI disorders that predispose to bleeding disorders (e.g. ulcerative colitis, Crohn’s disease, GI cancers or diverticulitis). Treatment of perioperative pain in the setting of CABG surgery. Concomitant use with aspirin, other NSAIDs and anticoagulants.
Acute Overdose
Symptoms: Lethargy, drowsiness, nausea, vomiting, epigastric pain, GI bleeding, anaphylactoid reactions. Rarely, HTN, acute renal failure, resp depression and coma.
Management: Symptomatic and supportive treatment. Emesis and/or activated charcoal (60-100 g in adults, 1-2 g/kg in childn) and/or osmotic cathartic may be indicated. If patient is comatose, having seizures or lacks the gag reflex, gastric lavage may be done if an endotracheal tube w/ cuff inflated is in place to prevent aspiration of gastric contents.
Innovators Monograph
You find simplified version here Camviz
FAQ
What is Camviz used for?
Camviz is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis and rheumatoid arthritis.
How does Camviz work?
Camviz works by stopping the body's production of a substance that causes pain, fever, and inflammation.
What are the common side effects of Camviz?
The common side effects of are include:
- diarrhea.
- constipation.
- gas.
- headache.
- dizziness.
- ringing in the ears.
Is Camviz a painkiller?
Camviz is a nonsteroidal anti-inflammatory drug used for the treatment of osteoarthritis and rheumatoid arthritis pain and inflammation.
When should be taken of Camviz?
Camviz is usually taken once or twice a day. Take Camviz at around the same time every day.
Is Camviz safe during pregnancy?
Camviz capsules are not recommended for use in pregnant women since safety has not been established in humans.Camviz should be used during pregnancy only if the possible benefit outweighs the possible risk to the unborn baby.
Is Camviz safe during breastfeeding?
Camviz passes through breast milk and may cause side effects in a child who is breastfed. It's not recommended to breastfeed while taking this medication.
Can I drink alcohol with Camviz?
Avoid drinking alcohol. It may increase your risk of stomach bleeding. Avoid taking aspirin while you are taking Camviz.
Can I drive after taking Camviz?
Camviz may cause drowsiness, dizziness, tiredness, and vision disturbances, do not drive or operate heavy machinery if you feel dizzy.
How long does Camviz take to work?
Camviz usually begins to work within 1 week, but in severe cases up to two weeks or even longer may pass before you begin to feel better.
Can I take Camviz at night?
Camviz was equally effective when administered in the morning or at night, evidence for the view that a single daily dose relieves symptoms for at least 24 hours.
Is Camviz a muscle relaxant?
Camviz helps relieve pain and swelling of various joints and muscles.
Can I take Camviz on an empty stomach?
You do not need to take Camviz with food. However, if you experience some stomach upset, Camviz can be taken with food. Ask your doctor or pharmacist if you have any other concerns about your diet and this medicine.
How quickly does Camviz work?
Camviz usually begins to work within 1 week, but in severe cases up to two weeks or even longer may pass before you begin to feel better.
Is Camviz good for back pain?
Camviz can provide effective relief of acute low-back pain with good toleration; it should be considered for use in the initial treatment of this condition.
Does Camviz cause weight gain?
Camviz can causes weight gain also with other side effects.
Can I take Camviz for a long time?
Camviz usually begins to work within 1 week, but in severe cases up to two weeks or even longer may pass before you begin to feel better.
Who should not take?
Camviz can increase your risk of fatal heart attack or stroke. Do not use Camviz just before or after heart bypass surgery . Camviz may also cause stomach or intestinal bleeding, which can be fatal.
What happens if I miss a dose?
Take Camviz as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose on Camviz?
Seek emergency medical attention.Overdose symptoms may include nausea, vomiting, stomach pain, black or bloody stools, or coughing up blood.