Canertinib
Canertinib Uses, Dosage, Side Effects, Food Interaction and all others data.
Canertinib is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo. Canertinib treatment significantly affects tumour metabolism, proliferation and hypoxia as determined by PET.
Trade Name | Canertinib |
Generic | Canertinib |
Canertinib Other Names | Canertinib |
Type | |
Formula | C24H25ClFN5O3 |
Weight | Average: 485.938 Monoisotopic: 485.162995603 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in breast cancer and lung cancer.
How Canertinib works
CI-1033 effectively inhibits the growth of esophageal squamous cell carcinoma which co-expresses both EGFR and HER2 with the inhibition of phosphorylation of both MAPK and AKT. Some studies suggest that CI-1033 holds significant clinical potential in esophageal cancer.
Innovators Monograph
You find simplified version here Canertinib