Captodiame
Captodiame Uses, Dosage, Side Effects, Food Interaction and all others data.
Captodiame, also known as captodiamine, is an antihistamine which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine. Captodiame has been suggested for use in preventing benzodiazepine withdrawal syndrome.
Trade Name | Captodiame |
Generic | Captodiame |
Captodiame Other Names | Captodiame |
Type | |
Formula | C21H29NS2 |
Weight | Average: 359.592 Monoisotopic: 359.174141313 |
Groups | Experimental |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Captodiame is indicated for the treatment of anxiety.
Toxicity
-TDLo oral 17mg/kg (human) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX). PMID: 13535337. -LD50 intraperitoneal 116mg/kg (mouse) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD. PMID: 13062090. -LD50 intravenous 72mg/kg (mouse) BEHAVIORAL: ATAXIA. PMID: 14109651.
Elimination Route
Renal.
Innovators Monograph
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